Clinical Profile of posterior segment in high Myopia.

Q3 Medicine
Raju Kaiti, Birkha Bogati, Ranjila Shyangbo, Simanta Khadka, Priya Bajgai
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引用次数: 0

Abstract

Background: Myopia is a growing global health concern, with prevalence surging, especially in East and Southeast Asia. The World Health Organization identifies high myopia as -5.00 diopter or less, carrying an elevated risk of irreversible blindness. In 2020, an estimated 2.6 billion people had myopia, projected to reach 4.7 billion by 2050, leading to a rise in complications like myopic maculopathy. This study, conducted in Nepal, where 47.16% of the population is myopic, aims to assess fundus and optic nerve changes in high myopia, examining associations with age, gender, axial length, and mean spherical error.

Methods: A prospective, cross sectional study was conducted by recruiting 98 high myopic eyes (defined as spherical equivalent of <-5.0 diopters (D) or axial length ≥ 26.00 mm). Colored Fundus photography was performed on viewing angle of 500 in different field of gazes following pupillary dilatation. Fundus photographs were graded by independent graders to evaluate for high myopic fundus and optic disc changes. Multinomial logistic regression was performed with axial length and mean spherical error as risk and myopic changes as dependent variable.

Results: In this study, tessellated fundus (57.1%) and peripapillary atrophy (40.8%) were the most common posterior segment changes in high myopic Nepalese subjects. High myopic features were seen in 45.9% of cases. Increase in axial length and mean spherical error was established as a risk factor for development of high myopic changes in the fundus.

Conclusions: In this study of the highly myopic Nepalese population visiting tertiary eye hospital, myopic changes such as tessellated fundus and peripapillary atrophy were frequent and were associated with axial length and mean spherical error.

高度近视患者后节的临床概况。
背景:近视是一个日益令人担忧的全球健康问题,发病率急剧上升,尤其是在东亚和东南亚地区。世界卫生组织将高度近视定义为-5.00屈光度或以下的近视,这种近视会增加不可逆转的失明风险。2020 年,估计有 26 亿人患有近视,预计到 2050 年将达到 47 亿,从而导致近视性黄斑病变等并发症的增加。尼泊尔的近视人口占总人口的 47.16%,本研究旨在评估高度近视患者的眼底和视神经变化,研究其与年龄、性别、轴向长度和平均球面误差的关系:方法:我们招募了 98 只高度近视眼(定义为球面等效度数为 0.1 的近视眼),进行了一项前瞻性横断面研究:在这项研究中,网状眼底(57.1%)和毛细血管周围萎缩(40.8%)是尼泊尔高度近视受试者最常见的眼后节变化。45.9%的病例具有高度近视特征。轴长和平均球面误差的增加被认为是眼底发生高度近视变化的风险因素:在这项针对到三级眼科医院就诊的尼泊尔高度近视人群进行的研究中,近视改变(如眼底黄斑和毛细血管周围萎缩)很常见,并且与轴长和平均球面误差有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
81
审稿时长
15 weeks
期刊介绍: The journal publishes articles related to researches done in the field of biomedical sciences related to all the discipline of the medical sciences, medical education, public health, health care management, including ethical and social issues pertaining to health. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews and meta-analysis. Editorial, Guest Editorial, Viewpoint and letter to the editor are solicited by the editorial board. Frequently Asked Questions (FAQ) regarding manuscript submission and processing at JNHRC.
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