EEG Spectral Power Changes in Patients With Dysexecutive Syndrome Following Cognitive Intervention

IF 2.6 3区心理学 Q2 BEHAVIORAL SCIENCES

Brain and Behavior Pub Date : 2024-11-22 DOI:10.1002/brb3.70148

Claire Lebely, Evelyne Lepron, Ines Bigarre, Caroline Hamery, Xavier De Boissezon, Sebastien Scannella

{"title":"EEG Spectral Power Changes in Patients With Dysexecutive Syndrome Following Cognitive Intervention","authors":"Claire Lebely, Evelyne Lepron, Ines Bigarre, Caroline Hamery, Xavier De Boissezon, Sebastien Scannella","doi":"10.1002/brb3.70148","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Acquired brain injury (ABI) leads to cognitive deficiencies, alteration of brain activity associated with an increase in slow-wave (delta and theta bands) power, and reduced fast-wave (alpha, beta, and gamma bands) power. To compensate for the cognitive deficits that impact autonomy and quality of life, patients in a chronic phase can benefit from cognitive intervention.</p>\n </section>\n \n <section>\n \n <h3> Objective</h3>\n \n <p>This study explores the effects of cognitive intervention on brain activity, measured by electroencephalography (EEG), and on executive functioning, assessed by the Test of Attentional Performance (TAP) battery.</p>\n </section>\n \n <section>\n \n <h3> Method</h3>\n \n <p>We provided an ecological rehabilitation intervention, simulating real-life tasks adapted for patients with chronic cognitive disorders. A single-case experimental design (SCED) assessed patients' performance in terms of correct responses percentage (CRs) and reaction times (RTs), and EEG spectral powers before and 1 month after the intervention. The TAP tasks included working memory (WM), divided attention (DA), inhibition (GO), and flexibility (FL). EEG frequency powers were also measured during resting states.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>One month after the intervention, significant improvements were observed in CRs and RTs for the FL task. Increases in all frequency band powers occurred during FL, WM, and DA tasks, except for alpha bands in DA. In the GO task, delta and gamma power also increased after the intervention. No significant changes were found during resting-state EEG. The results of this open study, without a control group, are preliminary.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>The effects of the therapy are mostly reflected by changes in mental FL performance and altered EEG patterns during cognitive tasks, particularly in slow and fast-frequency bands. We argue that cognitive intervention could amplify the compensatory mechanisms following brain damage and/or ease restoration mechanisms in the fast-frequency activity bands. Further SCEDs or studies with control groups are needed to confirm these findings and the role of EEG biomarkers in rehabilitation.</p>\n </section>\n </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 11","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/brb3.70148","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain and Behavior","FirstCategoryId":"102","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/brb3.70148","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Acquired brain injury (ABI) leads to cognitive deficiencies, alteration of brain activity associated with an increase in slow-wave (delta and theta bands) power, and reduced fast-wave (alpha, beta, and gamma bands) power. To compensate for the cognitive deficits that impact autonomy and quality of life, patients in a chronic phase can benefit from cognitive intervention.

Objective

This study explores the effects of cognitive intervention on brain activity, measured by electroencephalography (EEG), and on executive functioning, assessed by the Test of Attentional Performance (TAP) battery.

Method

We provided an ecological rehabilitation intervention, simulating real-life tasks adapted for patients with chronic cognitive disorders. A single-case experimental design (SCED) assessed patients' performance in terms of correct responses percentage (CRs) and reaction times (RTs), and EEG spectral powers before and 1 month after the intervention. The TAP tasks included working memory (WM), divided attention (DA), inhibition (GO), and flexibility (FL). EEG frequency powers were also measured during resting states.

Results

One month after the intervention, significant improvements were observed in CRs and RTs for the FL task. Increases in all frequency band powers occurred during FL, WM, and DA tasks, except for alpha bands in DA. In the GO task, delta and gamma power also increased after the intervention. No significant changes were found during resting-state EEG. The results of this open study, without a control group, are preliminary.

Conclusion

The effects of the therapy are mostly reflected by changes in mental FL performance and altered EEG patterns during cognitive tasks, particularly in slow and fast-frequency bands. We argue that cognitive intervention could amplify the compensatory mechanisms following brain damage and/or ease restoration mechanisms in the fast-frequency activity bands. Further SCEDs or studies with control groups are needed to confirm these findings and the role of EEG biomarkers in rehabilitation.

Abstract Image

查看原文本刊更多论文

认知干预后执行障碍综合征患者的脑电图频谱功率变化

背景：获得性脑损伤（ABI）会导致认知缺陷，改变大脑活动，使慢波（δ和θ波段）功率增加，快波（α、β和γ波段）功率降低。为了弥补影响自主性和生活质量的认知缺陷，慢性期患者可以从认知干预中获益：本研究探讨了认知干预对脑电图（EEG）测量的大脑活动和注意力测试（TAP）评估的执行功能的影响：方法：我们为慢性认知障碍患者提供了一种生态康复干预，模拟现实生活中的任务。我们采用单例实验设计（SCED）评估了患者在干预前和干预后一个月的正确反应百分比（CRs）、反应时间（RTs）和脑电图频谱功率。TAP 任务包括工作记忆 (WM)、分散注意 (DA)、抑制 (GO) 和灵活性 (FL)。此外，还测量了静息状态下的脑电图频谱功率：干预一个月后，FL 任务的 CRs 和 RTs 有了明显改善。在 FL、WM 和 DA 任务中，除 DA 中的α 频段外，所有频段的功率都有所提高。在 GO 任务中，干预后 delta 和 gamma 功率也有所增加。静息状态脑电图未发现明显变化。这项没有对照组的开放式研究结果是初步的：疗法的效果主要体现在智力FL表现的变化和认知任务期间脑电图模式的改变，特别是在慢频和快频段。我们认为，认知干预可以扩大脑损伤后的代偿机制和/或缓解快频段活动的恢复机制。要证实这些发现以及脑电图生物标志物在康复中的作用，还需要进一步的 SCED 或对照组研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Brain and Behavior BEHAVIORAL SCIENCES-NEUROSCIENCES

CiteScore

5.30

自引率

0.00%

发文量

352

审稿时长

14 weeks

期刊介绍： Brain and Behavior is supported by other journals published by Wiley, including a number of society-owned journals. The journals listed below support Brain and Behavior and participate in the Manuscript Transfer Program by referring articles of suitable quality and offering authors the option to have their paper, with any peer review reports, automatically transferred to Brain and Behavior. * [Acta Psychiatrica Scandinavica](https://publons.com/journal/1366/acta-psychiatrica-scandinavica) * [Addiction Biology](https://publons.com/journal/1523/addiction-biology) * [Aggressive Behavior](https://publons.com/journal/3611/aggressive-behavior) * [Brain Pathology](https://publons.com/journal/1787/brain-pathology) * [Child: Care, Health and Development](https://publons.com/journal/6111/child-care-health-and-development) * [Criminal Behaviour and Mental Health](https://publons.com/journal/3839/criminal-behaviour-and-mental-health) * [Depression and Anxiety](https://publons.com/journal/1528/depression-and-anxiety) * Developmental Neurobiology * [Developmental Science](https://publons.com/journal/1069/developmental-science) * [European Journal of Neuroscience](https://publons.com/journal/1441/european-journal-of-neuroscience) * [Genes, Brain and Behavior](https://publons.com/journal/1635/genes-brain-and-behavior) * [GLIA](https://publons.com/journal/1287/glia) * [Hippocampus](https://publons.com/journal/1056/hippocampus) * [Human Brain Mapping](https://publons.com/journal/500/human-brain-mapping) * [Journal for the Theory of Social Behaviour](https://publons.com/journal/7330/journal-for-the-theory-of-social-behaviour) * [Journal of Comparative Neurology](https://publons.com/journal/1306/journal-of-comparative-neurology) * [Journal of Neuroimaging](https://publons.com/journal/6379/journal-of-neuroimaging) * [Journal of Neuroscience Research](https://publons.com/journal/2778/journal-of-neuroscience-research) * [Journal of Organizational Behavior](https://publons.com/journal/1123/journal-of-organizational-behavior) * [Journal of the Peripheral Nervous System](https://publons.com/journal/3929/journal-of-the-peripheral-nervous-system) * [Muscle & Nerve](https://publons.com/journal/4448/muscle-and-nerve) * [Neural Pathology and Applied Neurobiology](https://publons.com/journal/2401/neuropathology-and-applied-neurobiology)