(001) facet-supported TiO2 facet heterojunction with abundant active sites and high-efficiency carrier separation for ultrasensitive SERS detection of antibiotic residues in foods
Yimin Tang , Shuang He , Xiuwen Wang , Bing Zhao , Xin Jiang , Libin Yang
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引用次数: 0
Abstract
Background
Antibiotic residues in animal-derived foods are seriously threatening human health and have attracted growing public attention. It is very important and valuable to carry out a rapid ultrasensitive detection of antibiotic residues, especially accurate identification based on molecular fingerprints.
Results
Here, a (001) facet-supported TiO2 facet heterojunction with abundant active sites (SF–TiO2) was developed as a surface-enhanced Raman scattering (SERS) substrate for ultrasensitive detection of antibiotic residues in milk and honey foods. Exposure of more (001) facets in SF-TiO2 can not only provide abundant surface-active sites for efficient chemical recognition of target molecules, but also form effective facet heterojunctions to achieve high-efficient carrier separation for charge transfer between substrate and molecule, which are together responsible for ultrasensitive SERS detection of target molecules with an enhancement factor of 1.3 × 107. The detection limit of enrofloxacin, enoxacin, ciprofloxacin and chloramphenicol residues in milk or honey reaches to 10−10-10−9 M, far lower than the EU standard. And, a simultaneous identification of multi-component residues in foods can be realized. The developed substrate exhibits excellent stability, anti-interference ability, and recyclability in the actual detection.
Significance
This work not only provides a novel SERS method for ultrasensitive detection of antibiotic residues in animal-derived foods, but also provides new ideas and concepts for the development of new-type semiconductor SERS substrates and their practical application.
期刊介绍:
Analytica Chimica Acta has an open access mirror journal Analytica Chimica Acta: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Analytica Chimica Acta provides a forum for the rapid publication of original research, and critical, comprehensive reviews dealing with all aspects of fundamental and applied modern analytical chemistry. The journal welcomes the submission of research papers which report studies concerning the development of new and significant analytical methodologies. In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and impact of the research and the extent to which it adds to the existing body of knowledge in analytical chemistry.