{"title":"Biomimetic Materials for Antibacterial Applications","authors":"Junjie Zhang, Heng Dong, Bing Liu, Dongliang Yang","doi":"10.1002/smll.202408543","DOIUrl":null,"url":null,"abstract":"The rise of antibiotic resistance poses a critical threat to global health, necessitating the development of novel antibacterial strategies to mitigate this growing challenge. Biomimetic materials, inspired by natural biological systems, have emerged as a promising solution in this context. These materials, by mimicking biological entities such as plants, animals, cells, viruses, and enzymes, offer innovative approaches to combat bacterial infections effectively. This review delves into the integration of biomimicry with materials science to develop antibacterial agents that are not only effective but also biocompatible and less likely to induce resistance. The study explores the design and function of various biomimetic antibacterial materials, highlighting their therapeutic potential in anti-infection applications. Further, the study provides a comprehensive summary of recent advancements in this field, illustrating how these materials have been engineered to enhance their efficacy and safety. The review also discusses the critical challenges facing the transition of these biomimetic strategies from the laboratory to clinical settings, such as scalability, cost-effectiveness, and long-term stability. Lastly, the study discusses the vast opportunities that biomimetic materials hold for the future of antibacterial therapy, suggesting that continued research and multidisciplinary collaboration will be essential to realize their full potential.","PeriodicalId":228,"journal":{"name":"Small","volume":"129 1","pages":""},"PeriodicalIF":13.0000,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Small","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1002/smll.202408543","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The rise of antibiotic resistance poses a critical threat to global health, necessitating the development of novel antibacterial strategies to mitigate this growing challenge. Biomimetic materials, inspired by natural biological systems, have emerged as a promising solution in this context. These materials, by mimicking biological entities such as plants, animals, cells, viruses, and enzymes, offer innovative approaches to combat bacterial infections effectively. This review delves into the integration of biomimicry with materials science to develop antibacterial agents that are not only effective but also biocompatible and less likely to induce resistance. The study explores the design and function of various biomimetic antibacterial materials, highlighting their therapeutic potential in anti-infection applications. Further, the study provides a comprehensive summary of recent advancements in this field, illustrating how these materials have been engineered to enhance their efficacy and safety. The review also discusses the critical challenges facing the transition of these biomimetic strategies from the laboratory to clinical settings, such as scalability, cost-effectiveness, and long-term stability. Lastly, the study discusses the vast opportunities that biomimetic materials hold for the future of antibacterial therapy, suggesting that continued research and multidisciplinary collaboration will be essential to realize their full potential.
期刊介绍:
Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments.
With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology.
Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.