Disparities in Receipt of Medications for Opioid Use Disorder Before and During the COVID-19 Pandemic in the US Veterans Health Administration.

Minhee L Sung, Casey León, Joel I Reisman, Kirsha S Gordon, Robert D Kerns, Wenjun Li, Weisong Liu, Avijit Mitra, Hong Yu, William C Becker
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Abstract

Background: Populations disproportionately impacted by the opioid epidemic are less likely to receive medications for opioid use disorder (MOUD; OUD). The COVID-19 pandemic exacerbated these disparities. We performed an ecological survey of subpopulations to compare differences in MOUD receipt among Veterans with OUD before versus during the pandemic.

Methods: Using 2 cross-sections of 2 time periods of national Veterans Health Administration electronic health record data, we calculated proportions of Veterans with any MOUD receipt by demographics, Elixhauser comorbidity index, and natural language processing (NLP)-derived substance use and social determinants of health in each time period. We evaluated differences in MOUD receipt before and during the pandemic by patient characteristics using Chi-square and Cohen's h for effect size.

Results: Among 62 195 patients with OUD before the pandemic, the proportion prescribed MOUD increased from 46.5% before to 47.5% (P = .0003) during the pandemic. Statistically significant increased receipt of MOUD was observed for patients who were ≥55 years, men, White, with Elixhauser comorbidity indices of 2 and ≥5, and with NLP-derived indicators of substance use. There was a decrease that did not achieve statistical significance in MOUD receipt from before to during the pandemic for patients who were women, Black, Latinx, and food insecure.

Conclusions: The proportions of patients with OUD prescribed MOUD increased from before to during the pandemic. However, Veterans who were women, Black, Latinx, and food insecure did not experience these increases. These patients may benefit from interventions such as targeted outreach efforts to improve MOUD engagement to reduce OUD harms.

美国退伍军人健康管理局在 COVID-19 大流行之前和期间接受阿片类药物使用障碍药物治疗的差异。
背景:受阿片类药物流行病影响过大的人群接受阿片类药物使用障碍(MOUD;OUD)药物治疗的可能性较低。COVID-19 大流行加剧了这些差异。我们对亚人群进行了生态调查,以比较患有 OUD 的退伍军人在大流行之前和期间接受 MOUD 治疗的差异:我们使用退伍军人健康管理局全国电子健康记录数据的两个时间段的横截面,计算了每个时间段内接受过任何 MOUD 的退伍军人的比例,并按人口统计学、Elixhauser 合并症指数、自然语言处理(NLP)得出的药物使用和健康的社会决定因素进行了分类。我们使用Chi-square和Cohen's h来评估大流行前和大流行期间患者特征在接受MOUD方面的差异:结果:在大流行前的 62 195 名 OUD 患者中,处方 MOUD 的比例从大流行前的 46.5%增至大流行期间的 47.5%(P = 0.0003)。据统计,年龄≥55 岁、男性、白种人、Elixhauser 合并症指数为 2 和≥5 以及具有 NLP 衍生药物使用指标的患者接受 MOUD 的比例明显增加。从大流行前到大流行期间,女性、黑人、拉丁裔和食物无保障的患者接受 MOUD 的比例有所下降,但未达到统计学意义:结论:从大流行之前到大流行期间,获得 MOUD 处方的 OUD 患者比例有所增加。然而,女性、黑人、拉丁裔和食物无保障的退伍军人的比例并没有增加。这些患者可能会从干预措施中获益,例如有针对性地开展外联工作,提高 MOUD 的参与度,从而减少 OUD 的危害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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