Exploring the hidden world of RNA viruses with a transformer-based tool.

Abstract

Hou and He et al.¹ developed a new RNA virus identification tool named LucaProt, a transformer-based bioinformatics software using sequence and structural characteristics of RNA-dependent RNA polymerases (RdRPs), which are essential for almost all RNA viruses. LucaProt can identify RdRPs from highly diverse RNA viruses, unveiling the hidden RNA virosphere.