Ancient genomes from the Tang Dynasty capital reveal the genetic legacy of trans-Eurasian communication at the eastern end of Silk Road.

IF 4.4 1区生物学 Q1 BIOLOGY

BMC Biology Pub Date : 2024-11-20 DOI:10.1186/s12915-024-02068-9

Minglei Lv, Hao Ma, Rui Wang, Hui Li, Xiangyu Zhang, Wenbo Zhang, Yuding Zeng, Ziwei Qin, Hongbo Zhai, Yiqiang Lou, Yukai Lin, Le Tao, Haifeng He, Xiaomin Yang, Kongyang Zhu, Yawei Zhou, Chuan-Chao Wang

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引用次数: 0

Abstract

Background: Ancient Chang'an in the Tang Dynasty (618-907 AD) was one of the world's largest and most populated cities and acted as the eastern end of the world-famous Silk Road. However, little is known about the genetics of Chang'an people and whether the Western Regions-related gene flows have been prevalent in this cosmopolitan city.

Results: Here, we present seven genomes from Xingfulindai (XFLD) sites dating to the Tang Dynasty in Chang'an. We observed that four of seven XFLD individuals (XFLD_1) were genetically homogenous with the Late Neolithic Wadian, Pingliangtai, and Haojiatai populations from the middle reaches of the Yellow River Basin (YR_LN), with no genetic influence from the Western Eurasian or other non-Yellow River-related lineages. The remaining three XFLD individuals were a mixture of YR_LN-related ancestry and ~ 3-15% Western Eurasian-related ancestry. Mixtures of XFLD_1 and Western Eurasian-related ancestry drove the main gradient of genetic variation in northern and central Shaanxi Province today.

Conclusions: Our study underlined the widespread distribution of the YR_LN-related ancestry alongside the Silk Road within the territory of China during the historical era and provided direct evidence of trans-Eurasian communication in Chang'an from a genetic perspective.

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来自唐朝都城的古代基因组揭示了丝绸之路东端跨欧亚大陆交流的基因遗产。

背景：唐代（公元 618-907 年）的古长安是世界上规模最大、人口最多的城市之一，也是举世闻名的丝绸之路的东端。然而，人们对长安人的遗传学知之甚少，也不知道与西域相关的基因流是否曾在这座国际大都市盛行：结果：在此，我们展示了来自唐代长安兴福林台（XFLD）遗址的七个基因组。我们观察到，7 个 XFLD 个体中有 4 个（XFLD_1）与黄河流域中游（YR_LN）新石器时代晚期的瓦店、平凉台和郝家台种群具有同源性，没有受到欧亚大陆西部或其他非黄河相关种群的遗传影响。其余三个 XFLD 个体是 YR_LN 相关祖先和约 3-15% 欧亚西部相关祖先的混合物。XFLD_1和欧亚西部相关祖先的混合体是当今陕西省北部和中部遗传变异的主要梯度：我们的研究强调了历史时期 YR_LN 相关祖先在中国境内丝绸之路沿线的广泛分布，并从遗传学角度提供了长安跨欧亚大陆交流的直接证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Biology 生物-生物学

CiteScore

7.80

自引率

1.90%

发文量

260

审稿时长

3 months

期刊介绍： BMC Biology is a broad scope journal covering all areas of biology. Our content includes research articles, new methods and tools. BMC Biology also publishes reviews, Q&A, and commentaries.