High-resolution spatial multiomic census of the human placenta

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2024-11-20 DOI:10.1038/s41591-024-03353-4

引用次数: 0

Abstract

The placenta has an essential role in maintaining a successful pregnancy, yet its molecular composition and functions remain poorly understood. We present a comprehensive spatially resolved single-cell multi-omic census and molecular architecture of the first trimester human placenta.

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人类胎盘的高分辨率空间多组学普查

胎盘在维持成功妊娠中起着至关重要的作用，但人们对它的分子组成和功能仍然知之甚少。我们展示了一个全面的空间分辨单细胞多组学普查和人类妊娠头三个月胎盘的分子结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.