Accelerating Parkinson’s Disease drug development with federated learning approaches

IF 6.7 1区 医学 Q1 NEUROSCIENCES
Amit Khanna, Jamie Adams, Chrystalina Antoniades, Bastiaan R. Bloem, Camille Carroll, Jesse Cedarbaum, Joshua Cosman, David T. Dexter, Marissa F. Dockendorf, Jeremy Edgerton, Laura Gaetano, Erkuden Goikoetxea, Derek Hill, Fay Horak, Elena S. Izmailova, Tairmae Kangarloo, Dina Katabi, Catherine Kopil, Michael Lindemann, Jennifer Mammen, Kenneth Marek, Kevin McFarthing, Anat Mirelman, Martijn Muller, Gennaro Pagano, M. Judith Peterschmitt, Jie Ren, Lynn Rochester, Sakshi Sardar, Andrew Siderowf, Tanya Simuni, Diane Stephenson, Christine Swanson-Fischer, John A. Wagner, Graham B. Jones
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引用次数: 0

Abstract

Parkinson’s Disease is a progressive neurodegenerative disorder afflicting almost 12 million people. Increased understanding of its complex and heterogenous disease pathology, etiology and symptom manifestations has resulted in the need to design, capture and interrogate substantial clinical datasets. Herein we advocate how advances in the deployment of artificial intelligence models for Federated Data Analysis and Federated Learning can help spearhead coordinated and sustainable approaches to address this grand challenge.

Abstract Image

利用联合学习方法加速帕金森病药物开发
帕金森病是一种进行性神经退行性疾病,困扰着近 1200 万人。由于人们对帕金森病复杂多样的病理、病因和症状表现有了更深入的了解,因此需要设计、捕捉和查询大量临床数据集。在此,我们倡导如何通过部署用于联合数据分析和联合学习的人工智能模型的进步,帮助率先采用协调、可持续的方法来应对这一巨大挑战。
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来源期刊
NPJ Parkinson's Disease
NPJ Parkinson's Disease Medicine-Neurology (clinical)
CiteScore
9.80
自引率
5.70%
发文量
156
审稿时长
11 weeks
期刊介绍: npj Parkinson's Disease is a comprehensive open access journal that covers a wide range of research areas related to Parkinson's disease. It publishes original studies in basic science, translational research, and clinical investigations. The journal is dedicated to advancing our understanding of Parkinson's disease by exploring various aspects such as anatomy, etiology, genetics, cellular and molecular physiology, neurophysiology, epidemiology, and therapeutic development. By providing free and immediate access to the scientific and Parkinson's disease community, npj Parkinson's Disease promotes collaboration and knowledge sharing among researchers and healthcare professionals.
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