Thermoacoustic CBE imaging for monitoring microwave ablation of the liver: A feasibility study

IF 3.5 2区物理与天体物理 Q2 PHYSICS, APPLIED

Applied Physics Letters Pub Date : 2024-11-20 DOI:10.1063/5.0242212

Lian Feng, Ling Song, Zeqi Yang, Jieni Song, Wanting Peng, Zhenru Wu, Lin Huang, Yan Luo

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引用次数: 0

Abstract

Microwave ablation is the most commonly used minimally invasive technique for thermal ablation of liver tumors, and accurate monitoring of the ablation area is crucial for evaluating treatment efficacy. While traditional imaging techniques play an important role in clinical monitoring, they still face several insurmountable challenges. Microwave-induced thermoacoustic imaging (TAI) has emerged as a promising modality for ablation detection due to its high resolution and deep imaging capabilities. To further enhance the effectiveness of TAI in ablation monitoring, we propose a technique based on thermoacoustic changes in backscattered energy (CBE) imaging. This method accurately delineates the liver ablation area by monitoring temperature variations before and after ablation. Experimental results show that thermoacoustic CBE imaging offers significant advantages over traditional TAI, achieving accuracies of 97.12% in ex vivo and 93.46% in in vivo experiments. Its superior resolution makes it an ideal choice for monitoring tissue damage during microwave ablation.

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用于监测肝脏微波消融的热声 CBE 成像：可行性研究

微波消融是最常用的肝脏肿瘤热消融微创技术，而准确监测消融区域对于评估治疗效果至关重要。虽然传统成像技术在临床监测中发挥着重要作用，但仍面临着一些难以克服的挑战。微波诱导热声成像（TAI）因其高分辨率和深度成像能力，已成为一种很有前景的消融检测模式。为了进一步提高热声成像在消融监测中的有效性，我们提出了一种基于热声变化反向散射能量（CBE）成像的技术。该方法通过监测消融前后的温度变化，准确划定肝脏消融区域。实验结果表明，热声 CBE 成像与传统的 TAI 相比具有显著优势，在体外实验和体内实验中的准确率分别达到 97.12% 和 93.46%。其卓越的分辨率使其成为监测微波消融过程中组织损伤的理想选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Physics Letters 物理-物理：应用

CiteScore

6.40

自引率

10.00%

发文量

1821

审稿时长

1.6 months

期刊介绍： Applied Physics Letters (APL) features concise, up-to-date reports on significant new findings in applied physics. Emphasizing rapid dissemination of key data and new physical insights, APL offers prompt publication of new experimental and theoretical papers reporting applications of physics phenomena to all branches of science, engineering, and modern technology. In addition to regular articles, the journal also publishes invited Fast Track, Perspectives, and in-depth Editorials which report on cutting-edge areas in applied physics. APL Perspectives are forward-looking invited letters which highlight recent developments or discoveries. Emphasis is placed on very recent developments, potentially disruptive technologies, open questions and possible solutions. They also include a mini-roadmap detailing where the community should direct efforts in order for the phenomena to be viable for application and the challenges associated with meeting that performance threshold. Perspectives are characterized by personal viewpoints and opinions of recognized experts in the field. Fast Track articles are invited original research articles that report results that are particularly novel and important or provide a significant advancement in an emerging field. Because of the urgency and scientific importance of the work, the peer review process is accelerated. If, during the review process, it becomes apparent that the paper does not meet the Fast Track criterion, it is returned to a normal track.