Nanozymes: a promising solution for dental antibacterial applications

IF 3.9 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
RSC Advances Pub Date : 2024-11-20 DOI:10.1039/D4RA07303G
Lipeng Liu, Yaoyuan Zhang, Tianjuan Ju, Xutao Chen, Xinwei Li and Li-an Wu
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引用次数: 0

Abstract

Dental diseases pose significant public health challenges globally, affecting millions with conditions exacerbated by microbial-induced inflammation. Traditional natural enzymes, despite their antibacterial and anti-inflammatory capabilities, are limited by operational stability and environmental sensitivity. This review explores the revolutionary realm of nanozyme-artificial enzymes made from nanomaterials-which offer enhanced stability, cost-effectiveness, and ease of modification. We discuss the advent of nanozymes since their first recognition in 2007, emphasizing their enzyme-mimicking capabilities and applications in dental medicine, particularly for dental caries, pulpitis, periodontitis and peri-implantitis. This paper presents a comprehensive analysis of nanozymes' classification, mechanisms, and emerging applications, shedding light on their potential to revolutionize dental antibacterial treatments and addressing current challenges and future perspectives in their development.

Abstract Image

纳米酶:牙科抗菌应用的理想解决方案
牙科疾病对全球公共卫生构成重大挑战,数百万人因微生物引起的炎症而病情加重。传统的天然酶尽管具有抗菌消炎能力,但却受到操作稳定性和环境敏感性的限制。本综述探讨了纳米酶--由纳米材料制成的人造酶--的革命性领域,这种酶具有更高的稳定性、成本效益和易改性。我们讨论了纳米酶自 2007 年首次被认识以来的发展历程,强调了它们的酶模拟能力和在牙科医学中的应用,特别是在龋齿、牙髓炎、牙周炎和种植体周围炎方面的应用。本文对纳米酶的分类、机制和新兴应用进行了全面分析,揭示了纳米酶彻底改变牙科抗菌治疗的潜力,并探讨了纳米酶目前面临的挑战和未来的发展前景。
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来源期刊
RSC Advances
RSC Advances chemical sciences-
CiteScore
7.50
自引率
2.60%
发文量
3116
审稿时长
1.6 months
期刊介绍: An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.
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