Laure Mondo, Amira Bendjama, Maxime Taghavi, Evelyne Maillart, Lucie Bienfait, Marie-Dominique Gazagnes, Philippe Clevenbergh
{"title":"Acute immuno-allergic tubulo-interstitial nephritis due to amoxicillin confirmed by rechallenge","authors":"Laure Mondo, Amira Bendjama, Maxime Taghavi, Evelyne Maillart, Lucie Bienfait, Marie-Dominique Gazagnes, Philippe Clevenbergh","doi":"10.1684/ndt.2024.92","DOIUrl":null,"url":null,"abstract":"<p><p>Acute kidney injury is a common drug adverse reaction and may concerned antibiotics. We report a case of an acute renal failure due to amoxicillin occurring twice in the same patient. Two mechanisms have been described for amoxicillin, with an immuno-allergic origin observed in our case. The diagnosis, supported by kidney biopsy, was confirmed by rechallenge with this patient.</p>","PeriodicalId":94153,"journal":{"name":"Nephrologie & therapeutique","volume":"20 6","pages":"603-607"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nephrologie & therapeutique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1684/ndt.2024.92","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Acute kidney injury is a common drug adverse reaction and may concerned antibiotics. We report a case of an acute renal failure due to amoxicillin occurring twice in the same patient. Two mechanisms have been described for amoxicillin, with an immuno-allergic origin observed in our case. The diagnosis, supported by kidney biopsy, was confirmed by rechallenge with this patient.
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