Honeybee Venom: A Potential Source of Anticancer Components.

IF 1 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Sabrina Xin Yi Khor, Kitiphong Khongphinitbunjong, Amorn Owatworakit, Siau Hui Mah, Yin-Quan Tang
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引用次数: 0

Abstract

Cancer is a deadly disease that has claimed millions of lives worldwide. Traditional cancer treatments, such as chemotherapy and radiation, have been used for many years but have become less favored due to drug resistance, lack of tumor selectivity, high costs, and various side effects, such as fatigue and hair loss. Many studies have reported that animal venoms, such as those from snakes, scorpions, and bees, contain bioactive peptides that can be synthesized into anti-- cancer peptides (ACPs), which offer a potential alternative to traditional cancer therapies. Apitherapy is an area of growing interest for the development of new cancer treatments using bee venom, which is a complex mixture of biologically active peptides, enzymes, bioactive amines, and nonpeptide components that have been found to have anti-cancer properties. By leveraging these bioactive peptides, researchers could develop ACPs that are more targeted towards cancer cells, reducing the risk of adverse side effects and improving patient outcomes. The use of bee venom components in targeting cancer could provide a more selective, effective, and affordable approach to cancer therapy. While further research is needed, the potential benefits of using bee venom components in cancer therapy are significant and could help improve the lives of cancer patients worldwide. This study aims to review the components of bee venom as potential cancer treatments.

蜜蜂毒液:抗癌成分的潜在来源
癌症是一种致命疾病,已夺去了全球数百万人的生命。传统的癌症治疗方法,如化疗和放疗,已使用多年,但由于耐药性、缺乏肿瘤选择性、费用高昂以及疲劳和脱发等各种副作用,已不再受到青睐。许多研究报告指出,蛇、蝎子和蜜蜂等动物的毒液中含有生物活性肽,可以合成抗癌肽(ACP),为传统癌症疗法提供了潜在的替代品。蜂毒是生物活性肽、酶、生物活性胺和非肽成分的复杂混合物,具有抗癌特性。通过利用这些生物活性肽,研究人员可以开发出对癌细胞更有针对性的 ACP,从而降低产生不良副作用的风险,改善患者的治疗效果。利用蜂毒成分靶向治疗癌症可以提供一种选择性更强、更有效、更经济的癌症治疗方法。虽然还需要进一步研究,但在癌症治疗中使用蜂毒成分的潜在益处是巨大的,有助于改善全球癌症患者的生活。本研究旨在回顾蜂毒成分作为潜在癌症疗法的情况。
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来源期刊
Protein and Peptide Letters
Protein and Peptide Letters 生物-生化与分子生物学
CiteScore
2.90
自引率
0.00%
发文量
98
审稿时长
2 months
期刊介绍: Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations. Protein & Peptide Letters focuses on: Structure Studies Advances in Recombinant Expression Drug Design Chemical Synthesis Function Pharmacology Enzymology Conformational Analysis Immunology Biotechnology Protein Engineering Protein Folding Sequencing Molecular Recognition Purification and Analysis
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