Li-Qi Liang, Xian-Hua He, Chun-Yan Wei, Jing-Xian Zhao, Qian Wu, Min Liang, Jun Li, Yan Luo, Wei-Feng Xu, Rui-Yun Yang
{"title":"Antimicrobial polyketides from an endophytic fungus <i>Arcopilus aureus</i> HJ-7 from <i>Ardisia mamillata</i> Hance.","authors":"Li-Qi Liang, Xian-Hua He, Chun-Yan Wei, Jing-Xian Zhao, Qian Wu, Min Liang, Jun Li, Yan Luo, Wei-Feng Xu, Rui-Yun Yang","doi":"10.1080/14786419.2024.2429119","DOIUrl":null,"url":null,"abstract":"<p><p>Eleven polyketide derivatives, including two new compounds, xanthoradone D (<b>1</b>) and arisochromophilone (<b>2</b>), were isolated from <i>Arcopilus aureus</i> HJ-7, a Chinese medicinal plant <i>Ardisia mamillata</i> Hance-associated fungus. Their structures were elucidated on the basis of spectroscopic analysis and ECD (Electronic Circular Dichroism) calculations. The antibacterial and antifungal activities of the compounds were evaluated. Compound <b>1</b> showed the significant inhibitory activity against <i>Staphylococcus aureus</i> and <i>Xanthomonas axonopodis pv.</i> citri (Hasse) Dye with the MIC (Minimum Inhibitory Concentration) value of 6.25 μg/mL, and <b>1</b> also showed strong antifungal activities against <i>Cochliobolus miyabeanus</i> and <i>Ceratocystis paradoxa</i> with the MIC value of 3.125 μg/mL.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"1-8"},"PeriodicalIF":1.9000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2024.2429119","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Eleven polyketide derivatives, including two new compounds, xanthoradone D (1) and arisochromophilone (2), were isolated from Arcopilus aureus HJ-7, a Chinese medicinal plant Ardisia mamillata Hance-associated fungus. Their structures were elucidated on the basis of spectroscopic analysis and ECD (Electronic Circular Dichroism) calculations. The antibacterial and antifungal activities of the compounds were evaluated. Compound 1 showed the significant inhibitory activity against Staphylococcus aureus and Xanthomonas axonopodis pv. citri (Hasse) Dye with the MIC (Minimum Inhibitory Concentration) value of 6.25 μg/mL, and 1 also showed strong antifungal activities against Cochliobolus miyabeanus and Ceratocystis paradoxa with the MIC value of 3.125 μg/mL.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
