A resurfaced sensor NLR confers new recognition specificity to non-MAX effectors

IF 9.3 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Integrative Plant Biology Pub Date : 2024-11-19 DOI:10.1111/jipb.13805

Tongtong Zhu, Xuefeng Wu, Guixin Yuan, Dongli Wang, Vijai Bhadauria, You-Liang Peng, Junfeng Liu, Xin Zhang

引用次数: 0

Abstract

Replacing the HMA domain of the rice (Oryza sativa) immune receptor RGA5 with that of the rice HMA DOMAIN-CONTAINING PROTEIN 120 (HMA120) creates a designer RGA5^HMA120 that confers resistance to Magnaporthe oryzae isolates expressing the non-MAX effector gene AVR-Pita, thus enabling the generation of new synthetic resistance genes.

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重新浮现的传感器 NLR 赋予非 MAX 效应器新的识别特异性。

将水稻（Oryza sativa）免疫受体RGA5的HMA结构域替换为水稻HMA结构域- containing PROTEIN 120 （HMA120）的结构域，创建了一个设计RGA5HMA120，该设计RGA5HMA120使表达非max效应基因AVR-Pita的Magnaporthe oryzae分离株具有抗性，从而能够产生新的合成抗性基因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Integrative Plant Biology 生物-生化与分子生物学

CiteScore

18.00

自引率

5.30%

发文量

220

审稿时长

3 months

期刊介绍： Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.