Lutfi A. Hasnowo , Alexander A. Garapatski , Nelson E. Villa , Maria S. Larkina , Ivan V. Lomov , Mekhman S. Yusubov
{"title":"Excitation functions for Sc radioisotopes production via (α,x) nuclear reactions on natural calcium up to 25 MeV","authors":"Lutfi A. Hasnowo , Alexander A. Garapatski , Nelson E. Villa , Maria S. Larkina , Ivan V. Lomov , Mekhman S. Yusubov","doi":"10.1016/j.radphyschem.2024.112361","DOIUrl":null,"url":null,"abstract":"<div><div>Scandium (Sc) radioisotopes have been attracting increasing attention in medical applications. <sup>47</sup>Sc, which has the potential for targeted radiotherapy, is quite promising as a candidate for theranostic pairing with the β<sup>+</sup>-emitting radioisotope <sup>43</sup>Sc or <sup>44g</sup>Sc. The excitation functions for producing <sup>43,44m,44g,46,47</sup>Sc through (α,x) reactions on natural calcium (Ca) up to an energy of 25 MeV were experimentally measured and critically compared with previous experimental reports and theoretical data obtained by EMPIRE-3.2.3 code and from TENDL-2021 library. The physical yields for producing of <sup>43,44m,44g,46,47</sup>Sc through (α,x) reactions on <sup>nat</sup>Ca were determined using the measured production cross-section of the radionuclides and the stopping powers.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"227 ","pages":"Article 112361"},"PeriodicalIF":2.8000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation Physics and Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969806X24008533","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Scandium (Sc) radioisotopes have been attracting increasing attention in medical applications. 47Sc, which has the potential for targeted radiotherapy, is quite promising as a candidate for theranostic pairing with the β+-emitting radioisotope 43Sc or 44gSc. The excitation functions for producing 43,44m,44g,46,47Sc through (α,x) reactions on natural calcium (Ca) up to an energy of 25 MeV were experimentally measured and critically compared with previous experimental reports and theoretical data obtained by EMPIRE-3.2.3 code and from TENDL-2021 library. The physical yields for producing of 43,44m,44g,46,47Sc through (α,x) reactions on natCa were determined using the measured production cross-section of the radionuclides and the stopping powers.
期刊介绍:
Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.