Two new phenolic glycosides from the rhizomes of Paris yunnanensis

Abstract

Phytochemical investigation on the rhizomes of Paris yunnanensis led to the isolation of two undescribed phenolic glycosides (1 and 2), and three known analogues (3-5). Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, MS, and UV. Among them, compounds 1 and 2 have a rare 4-O-β-D-apiofuranosyl group. The DPPH radical scavenging activities of the isolated compounds were evaluated and compound 3 exhibited moderate DPPH radical scavenging activity with an EC₅₀ value of 72.6 μM, while Vitamin C was used as the positive control (EC₅₀ = 24.6 μM).