Cambios longitudinales en el índice de ROX y el puntaje de HACOR en pacientes críticos con insuficiencia respiratoria aguda por COVID-19 que requirieron cánula nasal de alto flujo: estudio de cohorte retrospectivo

Acta Colombiana de Cuidado Intensivo Pub Date : 2024-10-01 DOI:10.1016/j.acci.2024.08.001

Izeth Sallas Rodríguez , Helman Diaz Ramírez , José Santacruz Arias , Javier Polo Díaz , Miguel Aguilar Schotborgh , Amilkar Almanza Hurtado , Nestor Lora Villamil , Diana Borré Naranjo , Wilfrido Coronell Rodríguez , José Rojas Suárez , Carmelo Dueñas Castell

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引用次数: 0

Abstract

Objectives

Validate the IROX and HACOR scores, including their deltas, in determining their success, defined as survival and the need for intubation.

Design

Retrospective cohort study involving 115 patients admitted to intensive care for acute hypoxemic respiratory failure (AHRF) and treated with high-flow nasal cannula (HFNC).

Materials and methods

IROX and HACOR scores were evaluated at the initiation of HFNC use and at 24 hours (delta).

Background

In patients with AHRF due to SARS-CoV-2, the study aimed to determine the success of HFNC by evaluating this index and score and their respective deltas at 24 hours.

Results

At 24 hours, the IROX was higher in the success group (6.53 [4.80-10.44] vs. 4.76 [4.11-5.90]) and the HACOR was lower (4 [2-6] vs. 6 [5-6.75]), both results being significant (p = < 0.001). The D-ROX was positively associated with survival (47.37 [-1.89-136.11] vs. 5.06 [-16.85-34.25]; p = 0.002), contrary to the D-HACOR (-25 [-66.67-0] vs. 0 [-16.67-16.67]; p = < 0.001). Multivariate analysis of D-IROX (HR = 0.99, 95%CI [0.99-1], p = 0.001) and D-HACOR (HR = 1.01, 95%CI [1-1.01], p = 0.001) indicated that both are valid predictors of survival and failure.

Conclusion

The IROX and HACOR scores at 24 hours, along with their deltas, are good predictors of success.

查看原文本刊更多论文

需要使用高流量鼻插管的 COVID-19 急性呼吸衰竭重症患者 ROX 指数和 HACOR 评分的纵向变化：一项回顾性队列研究。

目的验证 IROX 和 HACOR 评分，包括其 delta 值，以确定其成功率，即存活率和插管需求.设计回顾性队列研究，涉及 115 例因急性低氧血症呼吸衰竭（AHRF）入住重症监护室并接受高流量鼻插管（HFNC）治疗的患者.材料和方法在开始使用 HFNC 时和 24 小时（delta）时评估 IROX 和 HACOR 评分.结果 24 小时时，成功组的 IROX 较高（6.53 [4.80-10.44] vs. 4.76 [4.11-5.90]），HACOR 较低（4 [2-6] vs. 6 [5-6.75]），两个结果均有显著性（p = <0.001）。D-ROX 与生存率呈正相关（47.37 [-1.89-136.11] vs. 5.06 [-16.85-34.25]; p = 0.002），与 D-HACOR 相反（-25 [-66.67-0] vs. 0 [-16.67-16.67]; p = <0.001）。D-IROX（HR = 0.99，95%CI [0.99-1]，p = 0.001）和 D-HACOR（HR = 1.01，95%CI [1-1.01]，p = 0.001）的多变量分析表明，两者都是生存和失败的有效预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Colombiana de Cuidado Intensivo

CiteScore

0.50

自引率

0.00%

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