Behavioural Change Piecewise Constant Spatial Epidemic Models

Abstract

Human behaviour significantly affects the dynamics of infectious disease transmission as people adjust their behavior in response to outbreak intensity, thereby impacting disease spread and control efforts. In recent years, there have been efforts to incorporate behavioural change into spatio-temporal individual-level models within a Bayesian MCMC framework. In this past work, parametric spatial risk functions were employed, depending on strong underlying assumptions regarding disease transmission mechanisms within the population. However, selecting appropriate parametric functions can be challenging in real-world scenarios, and incorrect assumptions may lead to erroneous conclusions. As an alternative, non-parametric approaches offer greater flexibility. The goal of this study is to investigate the utilization of semi-parametric spatial models for infectious disease transmission, integrating an “alarm function” to account for behavioural change based on infection prevalence over time within a Bayesian MCMC framework. In this paper, we discuss findings from both simulated and real-life epidemics, focusing on constant piecewise distance functions with fixed change points. We also demonstrate the selection of the change points using the Deviance Information Criteria (DIC).