Pharmacodynamic approaches of phytoconstitutents in wound healing mechanisms

Abstract

The present review aims to provide the comprehensive study of pharmacodynamic actions of various phytoconstitutents that promote wound healing. Various medicinal plants have been used from centuries for treating various kinds of wounds. Different plants contain particular phytoconstitutents with an antioxidant, anti-inflammatory, immunostimulant and collagen synthesis activity on the wound. Many patents were filed on herbs that are frequently used in wound healing. Plants contain flavonoids, saponins, polysaacharides, alkaloids, volatile oil and terpenoids, etc and their active constituents such as eugenol, rutin, quercetin, kampferol, curcumin, α- terpineol, etc act on different phases of wound healing that helps to reduce inflammation, have scavenging activity and provide relief from pain. In conclusion, phytoconstitutents shows their promising effect on wound healing.