Diagnosis of fetal isolated cleft palate using assessment of the posterior hard palate angle.

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Ultrasound Pub Date : 2024-06-20 DOI:10.1177/1742271X241260220

Iglika Ivancheva Simeonova-Brachot

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引用次数: 0

Abstract

Objective: The study aims to evaluate the role of the posterior hard palate angle in the prenatal diagnosis of cleft palate.

Study design: Stored images of the axial transverse view of the fetal secondary palate, obtained at three-level obstetric ultrasounds, were used to evaluate the posterior border of the hard palate. The study population comprised 63 consecutive pregnancies of unaffected cases and 17 pregnancies suspected for a cleft palate without cleft lip, including 7 cases of cleft palate, 4 cases of high-arched palate, and 6 false-positive cases.

Results: The posterior angle of the hard palate was significantly larger in the cleft palate group than in the healthy controls and false-positive cases: 227° (±51°) vs 160° (±16°), p < 0.0001; and 173° ± 18°, p < 0.0001, respectively. Regression analysis revealed that reflex angle remained an independent risk factor for cleft palate (odds ratio, 58.67 (95% confidence interval 10-341)). The sensitivity and specificity of the posterior angle assessment were 73% and 96%, respectively.

Conclusions: The posterior hard palate angle could be an ultrasound marker of cleft palate without a cleft lip.

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通过评估硬腭后角诊断胎儿孤立性腭裂。

研究目的研究旨在评估硬腭后角在腭裂产前诊断中的作用：研究设计：利用三级产科超声检查获得的胎儿次腭轴向横切面的存储图像来评估硬腭后缘。研究对象包括 63 例未受影响的连续妊娠和 17 例怀疑有腭裂而无唇裂的妊娠，其中包括 7 例腭裂、4 例高拱腭和 6 例假阳性病例：结果：腭裂组硬腭后角明显大于健康对照组和假阳性病例：分别为227°（±51°） vs 160°（±16°），P < 0.0001；173° ± 18°，P < 0.0001。回归分析显示，反射角仍然是腭裂的独立风险因素（几率比为 58.67（95% 置信区间 10-341））。后角评估的敏感性和特异性分别为 73% 和 96%：结论：硬腭后角可作为无唇裂腭裂的超声标记。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： Ultrasound is the official journal of the British Medical Ultrasound Society (BMUS), a multidisciplinary, charitable society comprising radiologists, obstetricians, sonographers, physicists and veterinarians amongst others.