{"title":"Native kidney biopsy in pregnancy and postpartum: A single centre experience from India.","authors":"Shreya Srinivas Mondemu, Sreejith Parameswaran, Rajesh Nachiappa Ganesh, Anish Keepanasseril","doi":"10.1177/1753495X241290664","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>With the advances in medicine and imaging, renal biopsy is increasingly utilised for identifying pathologies during pregnancy.</p><p><strong>Methods: </strong>This retrospective observational study aimed to assess indications and complications among 32 women who underwent native renal biopsies during pregnancy and postpartum from 2015 to 2022.</p><p><strong>Results: </strong>The commonest indications for performing the biopsy were nephrotic syndrome and acute kidney injury during pregnancy or immediately postpartum. Most (62.5%) had biopsies performed in the antenatal period. Lupus nephritis was the most common finding on biopsy, and there were no procedure-related serious adverse effects. Most pregnancies were complicated by hypertensive disorders and preterm birth. All except six women with perinatal loss had healthy neonates.</p><p><strong>Conclusions: </strong>Even as kidney biopsy remains the gold standard for diagnosing renal pathologies, it should be reserved for women where management in pregnancy would be altered by the result.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X241290664"},"PeriodicalIF":0.8000,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11563491/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obstetric Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/1753495X241290664","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: With the advances in medicine and imaging, renal biopsy is increasingly utilised for identifying pathologies during pregnancy.
Methods: This retrospective observational study aimed to assess indications and complications among 32 women who underwent native renal biopsies during pregnancy and postpartum from 2015 to 2022.
Results: The commonest indications for performing the biopsy were nephrotic syndrome and acute kidney injury during pregnancy or immediately postpartum. Most (62.5%) had biopsies performed in the antenatal period. Lupus nephritis was the most common finding on biopsy, and there were no procedure-related serious adverse effects. Most pregnancies were complicated by hypertensive disorders and preterm birth. All except six women with perinatal loss had healthy neonates.
Conclusions: Even as kidney biopsy remains the gold standard for diagnosing renal pathologies, it should be reserved for women where management in pregnancy would be altered by the result.