Retinal Toxicity Secondary to Suprachoroidal Migration of Mitomycin-C.

IF 0.5 Q4 OPHTHALMOLOGY
Karim Dirani, Cesar Alfaro, Faisal Ridha Al-Timimi, Daniel Juzych, Pradeepa Yoganathan
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引用次数: 0

Abstract

Purpose: To report a case of suprachoroidal migration of mitomycin-C (MMC) with ensuing retinal toxicity after trabeculectomy. Methods: A case report of retinal toxicity is described with multimodal imaging. Results: A patient developed occlusion of the retinal and choroidal vasculature in a segmental fashion that could be explained by suprachoroidal diffusion. Fundus autofluorescence showed a stippled pattern over an area of hypofluorescence in the superonasal quadrant, and a late fluorescein angiogram image showed staining of the superonasal quadrant with dependent leakage toward the optic nerve and macula. Conclusions: MMC is commonly used in glaucoma-filtering surgical procedures, and few cases of postoperative posterior segment toxicity have been reported. To our knowledge, we are the first to describe suprachoroidal migration of MMC with subsequent retinal toxicity.

丝裂霉素-C在脉络膜上迁移引起的视网膜毒性
目的:报告一例小梁切除术后丝裂霉素-C(MMC)发生脉络膜上移并导致视网膜中毒的病例。方法:通过多模态成像描述一例视网膜毒性病例。结果一名患者的视网膜和脉络膜血管出现节段性闭塞,这可以用脉络膜上弥散来解释。眼底自动荧光显示眼底上象限低荧光区域上有条纹状图案,晚期荧光素血管造影图像显示眼底上象限染色,视神经和黄斑有依赖性渗漏。结论:MMC 常用于青光眼滤过手术,但很少有术后后节中毒的病例报道。据我们所知,我们是第一例描述 MMC 脉络膜上移并导致视网膜中毒的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.20
自引率
16.70%
发文量
0
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