The effect of occupational exposure to organic dust on lung function parameters among African industrial workers: a systematic review and meta-analysis.

IF 3 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Frontiers in Public Health Pub Date : 2024-11-01 eCollection Date: 2024-01-01 DOI:10.3389/fpubh.2024.1424315

Zemachu Ashuro, Berhanu Gidisa Debela, Chala Daba, Habtamu Endashaw Hareru, Samson Wakuma Abaya, Anthony L Byrne

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引用次数: 0

Abstract

Introduction: Inadequate ventilation and improper use of personal protective equipment are often observed in many occupational settings with a high risk of dust and other fine particle exposure. Workers who are exposed to dust at work may suffer from respiratory difficulties. Previous systematic reviews on organic dust exposure and its association with respiratory health outcomes did not provide a comprehensive assessment. Therefore, the objective of this systematic review and meta-analysis was to summarize the reported effects of organic dust exposure on lung function parameters among African industrial workers.

Methods: A compressive literature search was conducted in PubMed, MEDLINE, Google Scholar, Embase, the Web of Science, African Journals Online, and ScienceDirect databases to identify relevant studies for the review. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. The lung function indices including forced vital capacity (FVC), forced expiratory volume in the first second (FEV₁), the FEV₁/FVC ratio, and peak expiratory flow rate (PEFR) were obtained from primary studies and analyzed using STATA version 17. The I ² test was used to assess the heterogeneity of studies. We used a random-effects model to estimate the pooled standard mean difference in lung function indices between organic dust-exposed and non-exposed industrial workers. To analyze publication bias, funnel plots and Egger's test were applied.

Results: In this systematic review and meta-analysis, 32 studies involving 7,085 participants were included from 13,529 identified studies. The estimated mean differences with 95% confidence intervals were as follows: -0.53 [-0.83 to -0.36] L for FVC, -0.60 [-0.77 to -0.43] L for FEV₁, -0.43 [-0.57, -0.29] L for FEV₁/FVC, and -0.69 [-0.88 to -0.50] L/min for PEFR.

Conclusion: This systematic review and meta-analysis revealed that the lung function indices, such as FVC, FEV₁, FEV₁/FVC, and PEFR, were statistically significantly lower among organic dust-exposed industrial workers compared to non-exposed industrial workers. Therefore, effective dust control measures should be implemented to protect workers from exposure to organic dust.

Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024527139.

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有机粉尘职业暴露对非洲产业工人肺功能参数的影响：系统回顾和荟萃分析。

导言：在许多接触粉尘和其他微粒风险较高的职业环境中，经常会发现通风不足和个人防护设备使用不当的情况。在工作中接触粉尘的工人可能会出现呼吸困难。以往关于有机粉尘暴露及其与呼吸系统健康结果的关系的系统综述并未提供全面的评估。因此，本系统综述和荟萃分析的目的是总结报告的有机粉尘暴露对非洲产业工人肺功能参数的影响：方法：在 PubMed、MEDLINE、Google Scholar、Embase、Web of Science、African Journals Online 和 ScienceDirect 数据库中进行了压缩文献检索，以确定用于综述的相关研究。采用纽卡斯尔-渥太华量表（NOS）评估纳入研究的质量。从主要研究中获取肺功能指数，包括用力肺活量（FVC）、第一秒用力呼气量（FEV1）、FEV1/FVC 比值和呼气峰流速（PEFR），并使用 STATA 17 版进行分析。I 2 检验用于评估研究的异质性。我们使用随机效应模型来估算暴露于有机粉尘和未暴露于有机粉尘的产业工人之间肺功能指数的汇总标准平均值差异。为了分析发表偏倚，我们采用了漏斗图和 Egger 检验：在这项系统回顾和荟萃分析中，从 13529 项已确定的研究中纳入了 32 项研究，涉及 7085 名参与者。估计的平均差异及 95% 的置信区间如下：FVC为-0.53 [-0.83 to -0.36] L，FEV1为-0.60 [-0.77 to -0.43] L，FEV1/FVC为-0.43 [-0.57, -0.29] L，PEFR为-0.69 [-0.88 to -0.50] L/min：这项系统回顾和荟萃分析表明，与未接触有机粉尘的产业工人相比，接触有机粉尘的产业工人的肺功能指数，如 FVC、FEV1、FEV1/FVC 和 PEFR，在统计学上显著降低。因此，应采取有效的粉尘控制措施，保护工人免受有机粉尘的影响。系统综述注册：https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024527139。

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来源期刊

Frontiers in Public Health Medicine-Public Health, Environmental and Occupational Health

CiteScore

4.80

自引率

7.70%

发文量

4469

审稿时长

14 weeks

期刊介绍： Frontiers in Public Health is a multidisciplinary open-access journal which publishes rigorously peer-reviewed research and is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians, policy makers and the public worldwide. The journal aims at overcoming current fragmentation in research and publication, promoting consistency in pursuing relevant scientific themes, and supporting finding dissemination and translation into practice. Frontiers in Public Health is organized into Specialty Sections that cover different areas of research in the field. Please refer to the author guidelines for details on article types and the submission process.