Preventing Progression of Renal Disease: A New Method for Monitoring Body Fat Percentage in Predialysis Chronic Kidney Disease Patients

IF 3.2 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Pub Date : 2024-10-19 DOI:10.1016/j.nut.2024.112605

María del Rocío Jiménez-Mérida R.N., M.Sc., Ph.D. , José Manuel Alcaide-Leyva R.N., M.Sc., Ph.D. , Miguel Lopez-Lucena R.N. , Silvia Portero de la Cruz R.N., M.Sc., Ph.D. , Rafael Molina-Luque R.N., M.Sc., Ph.D. , Pablo Martínez-Angulo R.N., M.Sc., Ph.D.

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引用次数: 0

Abstract

Background and Aims

Chronic kidney disease (CKD) is a progressive condition affecting metabolic pathways and physiological mechanisms. In Spain, CKD prevalence has risen, increasing patients requiring renal replacement therapy (RRT). Managing nutritional status in advanced CKD (ACKD) patients is crucial as it influences disease progression and quality of life. This study aims to describe the nutritional status of predialysis patients at University Hospital Reina Sofia, Cordoba, Spain, and develop a quick and easy model for estimating body fat percentage without bioimpedance.

Methods and Results

This cross-sectional study, conducted from February to May 2023, involved 106 patients from the ACKD consultation at the University Hospital Reina Sofia. Inclusion criteria were stage 3 or 4 CKD patients who consented to participate. Data included demographic and anthropometric variables, with body composition assessed using a Tanita BC-545N bioimpedance analyzer.

The sample included 32 females (30.5%) and 73 males (69.5%), with an average BMI of 30.31 (SD 5.48). Significant findings were higher body fat percentage in women (37.82%) than men (27.86%; P < 0.001) and notable differences in waist circumference and waist-to-hip ratio between sexes. Multiple linear regression showed waist circumference, height, and sex as significant predictors of body fat percentage, with an intraclass correlation coefficient of 0.71 (95% CI = 0.59–0.79).

Conclusion

Accurately assessing body composition in CKD patients is crucial as traditional measures like BMI may not capture health risks effectively. The developed model offers a practical alternative to bioimpedance for estimating body fat percentage, potentially improving CKD management and patient outcomes. Further validation in diverse populations and integration with lifestyle interventions is needed.

查看原文本刊更多论文

预防肾病恶化：监测透析前慢性肾病患者体脂百分比的新方法。

背景和目的：慢性肾脏病（CKD）是一种影响代谢途径和生理机制的渐进性疾病。在西班牙，慢性肾脏病的发病率有所上升，需要接受肾脏替代治疗（RRT）的患者也随之增加。晚期慢性肾脏病（ACKD）患者的营养状况影响着疾病的进展和生活质量，因此对其营养状况的管理至关重要。本研究旨在描述西班牙科尔多瓦索菲亚王后大学医院透析前患者的营养状况，并开发一种无需生物阻抗即可估算体脂百分比的快速简便模型：这项横断面研究于 2023 年 2 月至 5 月进行，涉及索菲亚雷娜大学医院 ACKD 诊所的 106 名患者。纳入标准为同意参与的 3 期或 4 期 CKD 患者。数据包括人口统计学和人体测量变量，并使用Tanita BC-545N生物阻抗分析仪评估身体成分。样本包括 32 名女性（30.5%）和 73 名男性（69.5%），平均体重指数为 30.31（标清 5.48）。显著的发现是女性的体脂率（37.82%）高于男性（27.86%；P < 0.001），而且男女之间的腰围和腰臀比也有明显差异。多元线性回归结果显示，腰围、身高和性别是体脂率的重要预测因素，类内相关系数为 0.71 (95% CI = 0.59-0.79)：结论：准确评估 CKD 患者的身体成分至关重要，因为 BMI 等传统测量方法可能无法有效捕捉健康风险。所开发的模型为估算体脂百分比提供了生物阻抗的实用替代方法，有可能改善 CKD 管理和患者预后。还需要在不同人群中进一步验证，并与生活方式干预相结合。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition 医学-营养学

CiteScore

7.80

自引率

2.30%

发文量

300

审稿时长

60 days

期刊介绍： Nutrition has an open access mirror journal Nutrition: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Founded by Michael M. Meguid in the early 1980''s, Nutrition presents advances in nutrition research and science, informs its readers on new and advancing technologies and data in clinical nutrition practice, encourages the application of outcomes research and meta-analyses to problems in patient-related nutrition; and seeks to help clarify and set the research, policy and practice agenda for nutrition science to enhance human well-being in the years ahead.