Diagnostic performance of adult-based thyroid imaging reporting and data systems in pediatric thyroid carcinoma: a retrospective study.

IF 2.9 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

BMC Medical Imaging Pub Date : 2024-11-15 DOI:10.1186/s12880-024-01496-x

Wanying Li, Yiyan Du, Yao Wei, Ruie Feng, Ying Wang, Xiao Yang, Hongyan Wang, Jianchu Li

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引用次数: 0

Abstract

Background: Thyroid nodules diagnosed in children pose a greater risk of malignancy compared to those in adults. However, there is no ultrasound thyroid nodule evaluation system aimed at children. The objective of this research is to assess the diagnostic performance of the adult-based American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS) and Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) in pediatric thyroid carcinoma.

Methods: The preoperative ultrasound images of 177 thyroid lesions in 136 pediatric patients aged 18 or younger who underwent thyroid surgery or fine needle aspiration (FNA) at our center from July 2017 to July 2022 were reviewed. The sonographic characteristics of pediatric thyroid carcinoma were compared and analyzed in contrast to benign nodules. All the nodules were evaluated by the ACR-TIRADS and the C-TIRADS respectively.

Results: Ultrasound features such as solid composition (94.8%), hypoechogenicity or marked hypoechogenicity (94.8-95.7%) and microcalcification (78.3-84.3%) were more common in pediatric malignant nodules (P-values < 0.05). The areas under receiver operating characteristic curves (AUC) of the ACR-TIRADS and the C-TIRADS in diagnosing pediatric thyroid carcinoma were 0.903-0.906, 0.907-0.909 (P-value > 0.05). The interobserver agreement of both the ACR-TIRADS and the C-TIRADS was strong (weighted Kappa > 0.90).

Conclusions: Both the C-TIRADS and the ACR-TIRADS owned great diagnostic performance and strong interobserver agreement in diagnosing pediatric thyroid carcinoma. However, a more complete and specific ultrasound evaluation system for pediatric thyroid nodules is still needed.

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基于成人甲状腺成像报告和数据系统在小儿甲状腺癌中的诊断性能：一项回顾性研究。

背景：与成人甲状腺结节相比，儿童甲状腺结节的恶性风险更高。然而，目前还没有针对儿童的超声甲状腺结节评估系统。本研究旨在评估基于成人的美国放射学会甲状腺影像报告和数据系统（ACR-TIRADS）和中国甲状腺影像报告和数据系统（C-TIRADS）对小儿甲状腺癌的诊断性能：回顾性分析2017年7月至2022年7月在我中心接受甲状腺手术或细针穿刺（FNA）的136例18岁及以下小儿患者的177例甲状腺病变的术前超声图像。对比分析了小儿甲状腺癌与良性结节的声像图特征。所有结节分别按照 ACR-TIRADS 和 C-TIRADS 进行评估：结果：实性成分（94.8%）、低回声或明显低回声（94.8%-95.7%）和微钙化（78.3%-84.3%）等超声特征在小儿恶性结节中更为常见（P值为0.05）。ACR-TIRADS和C-TIRADS的观察者间一致性很好（加权卡帕>0.90）：结论：C-TIRADS和ACR-TIRADS在诊断小儿甲状腺癌方面都具有很好的诊断性能和很强的观察者间一致性。然而，我们仍然需要一个更完整、更特异的小儿甲状腺结节超声评估系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Medical Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.60

自引率

3.70%

发文量

198

审稿时长

27 weeks

期刊介绍： BMC Medical Imaging is an open access journal publishing original peer-reviewed research articles in the development, evaluation, and use of imaging techniques and image processing tools to diagnose and manage disease.