Copper-Catalyzed One-Pot Synthesis of N,N-4-Triphenylthiazol-2-amines

Abstract

Herein, we reported an efficient copper-catalyzed strategy for the synthesis of N,N-4-triphenylthiazol-2-amines from bromoacetophenone, phenylthiourea and iodobenzene. This method features good functional group tolerance, easy availability of starting materials and simplicity of operation, which provides an alternative method for the synthesis of 2-aminothiazoles.