Effect of Behavioral Activation on Stigma and Quality of Life in Patients With Advanced Esophageal and Gastric Cancer: A Randomized Controlled Trial.

IF 3.3 2区医学 Q2 ONCOLOGY

Psycho‐Oncology Pub Date : 2024-11-01 DOI:10.1002/pon.70021

Runze Huang, Han Ge, Guodong Nie, Anlong Li, Lijun Liu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

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引用次数: 0

Abstract

Background: Esophageal cancer and gastric cancer patients require researchers' attention to address and resolve the issue of stigma. The aim of this study was to investigate whether behavioral activation (BA), an emerging psychosocial intervention method, can mitigate the stigma experienced by these patients and enhance their quality of life (QoL).

Methods: One hundred fifty-three patients with advanced esophageal cancer and gastric cancer were recruited and randomly assigned to either the BA plus care as usual group (BA + CAU group) or the care as usual group (CAU group). Pre- and post-intervention questionnaires, including the Social Impact Scale (SIS), as well as all functional areas and global health and QoL modules from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30, version3).

Results: Generalized estimating equation analysis revealed that compared to usual care alone, combining BA with usual care significantly reduced stigma (time-by-group interaction, T1: β = -10.584, p < 0.001; T2: β = -22.619, p < 0.001) while improving physical, role, emotional, social functioning and global health and QoL particularly at T2 time point. Additionally, it also has the potential to decelerate the progressive decline of cognitive functioning. Furthermore, correlation analysis demonstrated a significant association between stigma levels and all functional areas as well as global health and QoL.

Conclusion: The issue of stigma among esophageal cancer and gastric cancer patients warrants increased attention due to its close relationship with patient QoL. This study presents a promising psychosocial intervention approach suitable for clinical application that deserves further promotion among cancer patients.

Trial registration: NCT06348940.

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行为激活对晚期食管癌和胃癌患者耻辱感和生活质量的影响：随机对照试验

背景：食管癌和胃癌患者需要研究人员的关注，以应对和解决污名化问题。本研究旨在探讨行为激活（BA）这一新兴的社会心理干预方法能否减轻这些患者的病耻感，并提高他们的生活质量（QoL）：招募了 153 名晚期食道癌和胃癌患者，并将他们随机分配到 BA 加常规护理组（BA + CAU 组）或常规护理组（CAU 组）。干预前后的问卷调查包括社会影响量表（SIS）以及欧洲癌症研究和治疗组织生活质量问卷（EORTC QLQ-C30，版本3）中的所有功能领域和全球健康及生活质量模块：结果：广义估计方程分析表明，与单纯的常规治疗相比，将 BA 与常规治疗相结合可显著减少耻辱感（时间与组间交互作用，T1：β = -10.584，p 结论：食管癌患者的耻辱感问题与其他癌症患者的耻辱感问题不同：食管癌和胃癌患者的污名化问题与患者的生活质量密切相关，因此应得到更多关注。本研究提出了一种适合临床应用的有前景的心理干预方法，值得在癌症患者中进一步推广：试验注册：NCT06348940。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psycho‐Oncology 医学-心理学

CiteScore

6.30

自引率

8.30%

发文量

220

审稿时长

3-8 weeks

期刊介绍： Psycho-Oncology is concerned with the psychological, social, behavioral, and ethical aspects of cancer. This subspeciality addresses the two major psychological dimensions of cancer: the psychological responses of patients to cancer at all stages of the disease, and that of their families and caretakers; and the psychological, behavioral and social factors that may influence the disease process. Psycho-oncology is an area of multi-disciplinary interest and has boundaries with the major specialities in oncology: the clinical disciplines (surgery, medicine, pediatrics, radiotherapy), epidemiology, immunology, endocrinology, biology, pathology, bioethics, palliative care, rehabilitation medicine, clinical trials research and decision making, as well as psychiatry and psychology. This international journal is published twelve times a year and will consider contributions to research of clinical and theoretical interest. Topics covered are wide-ranging and relate to the psychosocial aspects of cancer and AIDS-related tumors, including: epidemiology, quality of life, palliative and supportive care, psychiatry, psychology, sociology, social work, nursing and educational issues. Special reviews are offered from time to time. There is a section reviewing recently published books. A society news section is available for the dissemination of information relating to meetings, conferences and other society-related topics. Summary proceedings of important national and international symposia falling within the aims of the journal are presented.