Snus and cardiometabolic health markers among Swedish young adults.

IF 3 2区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Nicotine & Tobacco Research Pub Date : 2024-11-15 DOI:10.1093/ntr/ntae267

Anna Zettergren, Niklas Andersson, Göran Pershagen, Christian Lindh, Antonios Georgelis, Inger Kull, Erik Melén, Sandra Ekström, Petter Ljungman, Anna Bergström

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引用次数: 0

Abstract

Introduction: Snus is suggested as a risk factor for cardiometabolic disease, but little is known about health effects in young populations, particularly in women. We aimed to investigate associations between snus and cardiometabolic health markers among young men and women.

Method: This study was conducted within the BAMSE birth cohort and included participants followed up around 24 years (n=2256) and 26 years (n=1011). Snus use was assessed at 24 years by questionnaires. Cardiometabolic health markers were recorded at clinical examinations at 24 and 26 years. Associations between snus use and cardiometabolic markers were assessed by multivariable linear regression.

Results: Snus was used by 6.4% (n=81) among women and 21.9% (n=219) among men. Compared to no tobacco use, daily exclusive snus use among women at 24 years was associated with higher body mass index (BMI) (adjusted β: 1.93 kg/m2, 95% CI: 0.54, 3.33) and waist circumference (WC) (aβ: 3.80 cm, 95% CI: 0.41, 7.18) at 24 years, and with higher BMI (aβ: 2.73 kg/m2, 95% CI: 0.53-4.93) at 26 years. Among men, using ≥4 cans/week was associated with increased BMI (aβ: 2.48 kg/m2, 95% CI: 0.73, 4.24) and a tendency toward increased body fat (aβ: 2.31%, 95% CI: -0.53, 5.14) at 26 years. Snus use was not associated with glycemic status or blood pressure.

Conclusion: Our results suggest that snus is associated with increased BMI, and possibly other measures of adiposity, among young women and heavy using young men. Given the cross-sectional study design, the results should be interpreted with caution.

Implications: We found cross-sectional associations between snus use and measures of increased adiposity in a cohort of Swedish young adults, including BMI and waist circumference among women and BMI among heavy snus using men. We did not find associations between snus use and body fat %, glycemic status or blood pressure. This is one of few studies to investigate health effect of snus among both women and men as well as cardiometabolic health markers in young adults. Given the recent trends of increased snus use among young adults, our findings highlight the need for further research on snus on cardiometabolic health.

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瑞典年轻人中的斯努斯和心脏代谢健康指标。

导言：有人认为鼻烟是心血管代谢疾病的风险因素，但对年轻人，尤其是女性的健康影响却知之甚少。我们的目的是调查鼻烟与年轻男性和女性的心脏代谢健康指标之间的关系：这项研究是在 BAMSE 出生队列中进行的，包括 24 岁（n=2256）和 26 岁（n=1011）左右的随访参与者。通过问卷调查对参与者在 24 岁时使用 Snus 的情况进行了评估。24岁和26岁时的临床检查记录了心脏代谢健康指标。使用鼻烟与心脏代谢指标之间的关系通过多变量线性回归进行评估：结果：6.4%的女性（81人）和21.9%的男性（219人）使用鼻烟。与不吸烟相比，女性在24岁时每天只吸食鼻烟与较高的体重指数（BMI）（调整后β：1.93 kg/m2，95% CI：0.54，3.33）和腰围（WC）（aβ：3.80 cm，95% CI：0.41，7.18）有关，在26岁时与较高的体重指数（aβ：2.73 kg/m2，95% CI：0.53-4.93）有关。在男性中，使用量≥4罐/周与26岁时体重指数升高（aβ：2.48 kg/m2，95% CI：0.73，4.24）和体脂增加趋势（aβ：2.31%，95% CI：-0.53，5.14）有关。吸食鼻烟与血糖状况或血压无关：我们的研究结果表明，吸食鼻烟与年轻女性和大量吸食鼻烟的年轻男性的体重指数（BMI）增加有关，也可能与其他脂肪测量指标有关。鉴于研究设计为横断面研究，因此在解释结果时应谨慎：我们在一组瑞典年轻成年人中发现了使用鼻烟与肥胖程度增加之间的横断面关联，包括女性的体重指数和腰围以及大量使用鼻烟的男性的体重指数。我们没有发现使用鼻烟与体脂率、血糖状况或血压之间的关联。这是少数几项调查斯努斯对女性和男性健康影响以及青壮年心脏代谢健康指标的研究之一。鉴于近来年轻人越来越多地使用鼻烟的趋势，我们的研究结果凸显了进一步研究鼻烟对心脏代谢健康影响的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nicotine & Tobacco Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

8.10

自引率

10.60%

发文量

268

审稿时长

3-8 weeks

期刊介绍： Nicotine & Tobacco Research is one of the world''s few peer-reviewed journals devoted exclusively to the study of nicotine and tobacco. It aims to provide a forum for empirical findings, critical reviews, and conceptual papers on the many aspects of nicotine and tobacco, including research from the biobehavioral, neurobiological, molecular biologic, epidemiological, prevention, and treatment arenas. Along with manuscripts from each of the areas mentioned above, the editors encourage submissions that are integrative in nature and that cross traditional disciplinary boundaries. The journal is sponsored by the Society for Research on Nicotine and Tobacco (SRNT). It publishes twelve times a year.