Customized Corneal Cross-Linking with Microneedle-Mediated Riboflavin Delivery for Keratoconus Treatment (Adv. Mater. 46/2024)

IF 27.4 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Materials Pub Date : 2024-11-14 DOI:10.1002/adma.202470370

Mei Yang, Hongxian Pan, Tingting Chen, Xin Chen, Rui Ning, Qianfang Ye, Aodong Chen, Jiawei Li, Siheng Li, Nan Zhao, Yue Wu, Xueyu Fu, Keith M. Meek, Lingxin Chen, Xiaoying Wang, Zhongxing Chen, Xingtao Zhou, Jinhai Huang

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Abstract

Customized Corneal Cross-Linking

ln article number 2408136, Zhongxing Chen, Xingtao Zhou, Jinhai Huang, and co-workers introduce an innovative customized corneal cross-linking (CXL) therapy employing microneedles (MNs) for precise riboflavin (RF) delivery achieves notable CXL effects comparable to conventional epi-off CXL protocol and enhances visual function by flattening the corneal curvature in the treated zone. The frontispiece metaphorically represents the customized CXL process as being skillfully manipulated by magicians, highlighting the precision and efficacy of using MNs to deliver RF directly into the stroma and reinforce specific corneal zone.

Abstract Image

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利用微针介导核黄素递送定制角膜交联治疗角膜炎（Adv. Mater. 46/2024）

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来源期刊

Advanced Materials 工程技术-材料科学：综合

CiteScore

43.00

自引率

4.10%

发文量

2182

审稿时长

2 months

期刊介绍： Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.