Association between gender diversity and substance use experimentation in early adolescents

IF 3.9 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2024-10-29 DOI:10.1016/j.drugalcdep.2024.112473

Iris Y. Shao , Patrick Low , Shirley Sui , Christopher D. Otmar , Kyle T. Ganson , Alexander Testa , Glenn-Milo Santos , Jinbo He , Fiona C. Baker , Jason M. Nagata

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引用次数: 0

Abstract

Background

Gender diversity, encompassing gender identity beyond traditional binary frameworks, has been associated with substance use during adolescence. However, there is a paucity of studies that consider different dimensions of gender diversity. This study investigates associations between multiple dimensions of gender diversity and substance experimentation in early adolescents.

Methods

Data from 10,092 adolescents aged 12–13 years from the Adolescent Brain Cognitive Development (ABCD) study were used to assess the relationship between gender diversity and substance experimentation. Gender diversity was measured using multiple dimensions, including identity (transgender), felt gender (congruence between gender identity and assigned sex), gender non-contentedness (dissatisfaction with one’s gender), gender expression (adherence to gender expression norms), and place on the gender spectrum (masculine to feminine). Substance use was evaluated using self-reported lifetime and new experimentation (past year) of alcohol, nicotine, and cannabis use. Logistic regression models adjusted for sociodemographic factors were analyzed.

Results

More gender-diverse responses for felt gender, gender non-contentedness, gender expression, and gender spectrum were associated with higher odds of lifetime alcohol experimentation. More gender-diverse responses for gender identity and gender non-contentedness were associated with higher odds of new nicotine experimentation, and more gender-diverse responses for gender identity, felt gender, gender non-contentedness, and gender expression were associated with higher odds of lifetime and new cannabis experimentation.

Conclusion

Gender diversity is differentially associated with new and lifetime substance experimentation in early adolescence. Different dimensions of gender diversity may be uniquely associated with substance use behaviors, highlighting the need for targeted interventions in gender-diverse adolescents.

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青少年性别多样性与尝试使用药物之间的关系。

背景：性别多样性（包括超越传统二元框架的性别认同）与青春期药物使用有关。然而，很少有研究考虑到性别多样性的不同层面。本研究调查了早期青少年性别多样性的多个方面与药物试验之间的关联：研究使用了来自青少年大脑认知发展（ABCD）研究的 10,092 名 12-13 岁青少年的数据，以评估性别多样性与药物尝试之间的关系。性别多样性采用多个维度进行测量，包括身份（变性人）、感觉性别（性别身份与分配性别之间的一致性）、性别无倾向性（对自己的性别不满意）、性别表达（遵守性别表达规范）以及在性别光谱中的位置（从男性化到女性化）。物质使用情况通过自我报告的终生和新尝试（过去一年）使用酒精、尼古丁和大麻的情况进行评估。对调整了社会人口学因素的逻辑回归模型进行了分析：结果：对感觉到的性别、性别无倾向性、性别表达和性别谱系的性别多样性回答越多，则终生尝试饮酒的几率越高。对性别认同和性别无倾向性的性别多元化反应越多，新尝试尼古丁的几率越高；对性别认同、感觉到的性别、性别无倾向性和性别表达的性别多元化反应越多，终生尝试大麻和新尝试大麻的几率越高：结论：在青春期早期，性别多样性与新的和终生的药物尝试有着不同的关联。性别多样性的不同方面可能与药物使用行为有独特的关联，这突出表明需要对性别多样性青少年进行有针对性的干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.