Clinical Experiences Using CyberKnife for Large-Volume Meningiomas: A Preliminary Study.

Yonghun Song, Kyeong-O Go
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Abstract

Background: This preliminary study evaluates the safety and efficacy of CyberKnife radiosurgery (CKRS) for large-volume meningiomas (≥10 cm³), where surgical options may be limited due to tumor location or patient health conditions.

Methods: We retrospectively analyzed 18 patients with meningiomas treated with CKRS at Gyeongsang National University Hospital between 2010 and 2020. Tumor control and survival rates were evaluated, with follow-up imaging performed regularly.

Results: CKRS achieved a 5-year overall survival rate of 92.3% and a 5-year tumor control rate of 93.8%. Symptomatic peritumoral edema occurred in 61.1% of patients, with 16.7% requiring surgical intervention.

Conclusion: CKRS appears to be a promising option for patients with large meningiomas, showing good tumor control and manageable complications. Further studies with larger cohorts are necessary to confirm these findings.

使用 CyberKnife 治疗大体积脑膜瘤的临床经验:初步研究
背景:这项初步研究评估了CyberKnife放射外科手术(CKRS)治疗大体积脑膜瘤(≥10 cm³)的安全性和有效性:我们对2010年至2020年间在庆尚大学医院接受CKRS治疗的18例脑膜瘤患者进行了回顾性分析。评估了肿瘤控制率和存活率,并定期进行随访成像:CKRS的5年总生存率为92.3%,5年肿瘤控制率为93.8%。61.1%的患者出现症状性瘤周水肿,其中16.7%需要手术干预:结论:对于大脑膜瘤患者来说,CKRS似乎是一种很有前途的选择,它显示出良好的肿瘤控制效果和可控的并发症。为了证实这些研究结果,有必要进行更大规模的研究。
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