Long Axial Field of View PET/CT: Technical Aspects in Cardiovascular Diseases

IF 4.6 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Seminars in nuclear medicine Pub Date : 2025-01-01 DOI:10.1053/j.semnuclmed.2024.10.009

Tonantzin Samara Martinez-Lucio MD , Oscar Isaac Mendoza-Ibañez MD , Wanling Liu MD , Samaneh Mostafapour MSc , Zekai Li MSc , Laura Providência MSc , Giordana Salvi de Souza MSc , Philipp Mohr MSc , Magdalena M. Dobrolinska MD, PhD , Bram van Leer MD , Hendrea S.A. Tingen MD , Joyce van Sluis PhD , Charalampos Tsoumpas PhD , Andor W.J.M. Glaudemans MD, PhD , Klaas Pieter Koopmans MD, PhD , Adriaan A. Lammertsma PhD , Riemer H.J.A. Slart MD, PhD

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引用次数: 0

Abstract

Positron emission tomography / computed tomography (PET/CT) plays a pivotal role in the assessment of cardiovascular diseases (CVD), particularly in the context of ischemic heart disease. Nevertheless, its application in other forms of CVD, such as infiltrative, infectious, or inflammatory conditions, remains limited. Recently, PET/CT systems with an extended axial field of view (LAFOV) have been developed, offering greater anatomical coverage and significantly enhanced PET sensitivity. These advancements enable head-to-pelvis imaging with a single bed position, and in systems with an axial field of view (FOV) of approximately 2 meters, even total body (TB) imaging is feasible in a single scan session. The application of LAFOV PET/CT in CVD presents a promising opportunity to improve systemic cardiovascular assessments and address the limitations inherent to conventional short axial field of view (SAFOV) devices. However, several technical challenges, including procedural considerations for LAFOV systems in CVD, complexities in data processing, arterial input function extraction, and artefact management, have not been fully explored. This review aims to discuss the technical aspects of LAFOV PET/CT in relation to CVD by highlighting key opportunities and challenges and examining the impact of these factors on the evaluation of most relevant CVD.

查看原文本刊更多论文

长轴视场 PET/CT：心血管疾病的技术方面。

正电子发射断层扫描/计算机断层扫描（PET/CT）在评估心血管疾病（CVD），尤其是缺血性心脏病方面发挥着举足轻重的作用。然而，它在其他形式的心血管疾病（如浸润性、感染性或炎症性疾病）中的应用仍然有限。最近，具有扩展轴向视场（LAFOV）的 PET/CT 系统应运而生，可提供更大的解剖覆盖范围并显著提高 PET 的灵敏度。在轴向视场（FOV）约为 2 米的系统中，甚至可以在单次扫描中进行全身（TB）成像。LAFOV PET/CT 在心血管疾病中的应用为改善全身心血管评估和解决传统短轴向视场 (SAFOV) 设备固有的局限性提供了一个大有可为的机会。然而，一些技术挑战，包括 LAFOV 系统在心血管疾病中的程序考虑、数据处理的复杂性、动脉输入功能提取和伪影管理，尚未得到充分探讨。本综述旨在讨论 LAFOV PET/CT 与心血管疾病相关的技术方面，强调关键的机遇和挑战，并研究这些因素对最相关心血管疾病评估的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in nuclear medicine 医学-核医学

CiteScore

9.80

自引率

6.10%

发文量

审稿时长

14 days

期刊介绍： Seminars in Nuclear Medicine is the leading review journal in nuclear medicine. Each issue brings you expert reviews and commentary on a single topic as selected by the Editors. The journal contains extensive coverage of the field of nuclear medicine, including PET, SPECT, and other molecular imaging studies, and related imaging studies. Full-color illustrations are used throughout to highlight important findings. Seminars is included in PubMed/Medline, Thomson/ISI, and other major scientific indexes.