Sources and Methods for the Production of Xyloglucan, a Promising Stimulus-Sensitive Biopolymer: A Review.

IF 4.7 3区 工程技术 Q1 POLYMER SCIENCE
Polymers Pub Date : 2024-10-28 DOI:10.3390/polym16213022
Elena O Bakhrushina, Victor S Pyzhov, Jana A Yuntunen, Alexander S Gulenkov, Shoyad D Arislanov, Ksenia V Eremeeva, Anastasiya V Belyatskaya, Natalia B Demina, Ivan I Krasnyuk, Ivan I Krasnyuk
{"title":"Sources and Methods for the Production of Xyloglucan, a Promising Stimulus-Sensitive Biopolymer: A Review.","authors":"Elena O Bakhrushina, Victor S Pyzhov, Jana A Yuntunen, Alexander S Gulenkov, Shoyad D Arislanov, Ksenia V Eremeeva, Anastasiya V Belyatskaya, Natalia B Demina, Ivan I Krasnyuk, Ivan I Krasnyuk","doi":"10.3390/polym16213022","DOIUrl":null,"url":null,"abstract":"<p><p>Xyloglucan is a highly promising 'green' polymer that has found its application in the food and pharmaceutical industries. Due to its molecular structure similarity to mucin, it has remarkable mucoadhesion properties, which has led to a high research interest in this excipient for the development of transmucosal delivery systems. Thermosensitivity is another promising property of xyloglucan derivatives, which is mainly exhibited by synthetic block copolymers such as pluronics and PLGA derivatives. Delivery systems whose mechanism of active ingredient release is based on temperature sensitivity are widely used in many medical fields, ranging from antitumour therapy to intranasal delivery. Thus, conducting research on the possibility of obtaining and using a new mucoadhesive, fully biocompatible and affordable polymer-xyloglucan-is a promising task.</p>","PeriodicalId":20416,"journal":{"name":"Polymers","volume":"16 21","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11548392/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymers","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/polym16213022","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0

Abstract

Xyloglucan is a highly promising 'green' polymer that has found its application in the food and pharmaceutical industries. Due to its molecular structure similarity to mucin, it has remarkable mucoadhesion properties, which has led to a high research interest in this excipient for the development of transmucosal delivery systems. Thermosensitivity is another promising property of xyloglucan derivatives, which is mainly exhibited by synthetic block copolymers such as pluronics and PLGA derivatives. Delivery systems whose mechanism of active ingredient release is based on temperature sensitivity are widely used in many medical fields, ranging from antitumour therapy to intranasal delivery. Thus, conducting research on the possibility of obtaining and using a new mucoadhesive, fully biocompatible and affordable polymer-xyloglucan-is a promising task.

生产木聚糖这种前景看好的刺激敏感型生物聚合物的来源和方法:综述。
木聚糖是一种极具发展前景的 "绿色 "聚合物,已在食品和制药行业得到应用。由于其分子结构与粘蛋白相似,因此具有显著的粘附特性,这使得人们对这种用于开发经粘膜给药系统的辅料产生了浓厚的研究兴趣。热敏性是木聚糖衍生物的另一个有前途的特性,主要表现在合成嵌段共聚物上,如 pluronics 和 PLGA 衍生物。以温度敏感性为有效成分释放机制的给药系统被广泛应用于从抗肿瘤治疗到鼻内给药等多个医学领域。因此,研究获得和使用一种新型粘液粘附性、完全生物相容性和经济实惠的聚合物--木聚糖--的可能性是一项大有可为的任务。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Polymers
Polymers POLYMER SCIENCE-
CiteScore
8.00
自引率
16.00%
发文量
4697
审稿时长
1.3 months
期刊介绍: Polymers (ISSN 2073-4360) is an international, open access journal of polymer science. It publishes research papers, short communications and review papers. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Polymers provides an interdisciplinary forum for publishing papers which advance the fields of (i) polymerization methods, (ii) theory, simulation, and modeling, (iii) understanding of new physical phenomena, (iv) advances in characterization techniques, and (v) harnessing of self-assembly and biological strategies for producing complex multifunctional structures.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信