Mental health disorder in chronic liver disease: a questionnaire survey.

IF 3.2 3区医学 Q2 PSYCHIATRY

Frontiers in Psychiatry Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI:10.3389/fpsyt.2024.1469372

Jiang Long, Xiong Pei, Wei Jiang, Xiaoling Wang, Dongbo Wu, Xiangdong Tang, Taoyou Zhou

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引用次数: 0

Abstract

Background: The mental health of patients with chronic liver disease (CLD) warrants greater attention and understanding, especially concerning its risk factors.

Method: Patients from our hospital's hepatology clinic were consecutively enrolled and completed a questionnaire assessing anxiety, depression, and sleep quality using the GAD-7, PHQ-9, and PSQI scales, respectively. Reliability and validity were evaluated with Cronbach's α and Kaiser-Meyer-Olkin (KMO). Continuous and categorical variables were analyzed using the Mann-Whitney U and Chi-square tests. Univariate and multivariate logistic regression were used to identify risk factors, while restricted cubic spline (RCS) were used to explored non-linear associations. Subgroup analyses were stratified by sex, age, and education.

Result: A total of 1030 questionnaires were collected, and after quality control, 1003 were included. 56.2% (564/1003), 53.2% (534/1003), and 67.4% (676/1003) individuals had anxiety, depression, and sleep disorders. Differences in age, gender, and education level were observed (P<0.05). Subgroup analysis showed similar demographic trends. Univariate and multivariate regression analysis found age negatively correlated with anxiety (OR=0.98, 95%CI=0.97-0.99, P=0.02) and depression (OR=0.98, 95%CI=0.96-0.99, P<0.001), but positively correlated with sleep disorders (OR=1.03, 95%CI= 1.01-1.05, P< 0.001); males are less prone to anxiety (OR=0.68, 95%CI=0.52-0.88, P=0.004) and sleep disorders (OR=0.72, 95%CI: 0.55-0.94, P=0.02); university degree is more susceptible to depression (OR=1.36, 95%CI=1.04-1.77, P=0.02) and anxiety (OR=1.45, 95%CI=1.11-1.89, P=0.007). RCS analysis suggested a linear relationship between the age and affective disorders among different population.

Conclusion: Young individuals, female, and those with higher education are more vulnerable to mental health, warranting increased attention.

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慢性肝病患者的心理健康障碍：一项问卷调查。

背景：慢性肝病（CLD）患者的心理健康需要得到更多的关注和了解，尤其是有关其风险因素的问题：方法：连续招募本院肝病门诊的患者，并使用 GAD-7、PHQ-9 和 PSQI 量表分别填写一份评估焦虑、抑郁和睡眠质量的问卷。信度和效度采用 Cronbach's α 和 Kaiser-Meyer-Olkin (KMO) 进行评估。连续变量和分类变量采用 Mann-Whitney U 和 Chi-square 检验进行分析。单变量和多变量逻辑回归用于识别风险因素，而限制性立方样条曲线（RCS）则用于探索非线性关联。按性别、年龄和教育程度进行了分组分析：共收集了 1030 份问卷，经过质量控制后，纳入了 1003 份问卷。56.2%（564/1003）、53.2%（534/1003）和 67.4%（676/1003）的人患有焦虑症、抑郁症和睡眠障碍。观察到年龄、性别和受教育程度的差异（PP=0.02）和抑郁（OR=0.98，95%CI=0.96-0.99，PP< 0.001）；男性较不易患焦虑症（OR=0.68，95%CI=0.52-0.88，P=0.004）和睡眠障碍（OR=0.72，95%CI：0.55-0.94，P=0.02）；大学学历更易患抑郁症（OR=1.36，95%CI=1.04-1.77，P=0.02）和焦虑症（OR=1.45，95%CI=1.11-1.89，P=0.007）。RCS分析表明，在不同人群中，年龄与情感障碍之间存在线性关系：结论：年轻人、女性和受过高等教育的人更容易受到精神健康问题的影响，应引起更多关注。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Psychiatry Medicine-Psychiatry and Mental Health

CiteScore

6.20

自引率

8.50%

发文量

2813

审稿时长

14 weeks

期刊介绍： Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.