Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial.

IF 1.3 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM
Jianming Zhou, Xiaoning Gao, Dandan Zhang, Chuanwu Jiang, Wenbing Yu
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引用次数: 0

Abstract

Obesity resulting from long-term sedentary a significant threat to human health. This study explores the effects of exercise snack intervention on body composition and plasma metabolomics in sedentary obese adults. Participants in the snack group were subjected to 4 days of sprint exercises by stair-climbing per week for 12 weeks. Systemic and regional fat mass, epicardial adipose tissue (EAT), abdominal visceral (AVFA) and subcutaneous (ASFA) fat area and plasma metabolomics data were measured before and after intervention. A higher improvement of EAT, AVFA and ASFA in the snack group compared to that in the control group, with a significant interaction effect (p < 0.05). The key differential metabolites between the two groups include isoleucine, glycine and serine. The proposed exercise snack effectively reduced the amount of AVFA and EAT. The change in body composition may be associated with the altered pathways of isoleucine, glycine, and serine metabolism.

通过运动零食干预打破久坐对久坐肥胖成人身体成分和血浆代谢组学的影响:随机对照试验。
长期久坐导致的肥胖是对人类健康的重大威胁。本研究探讨了运动零食干预对久坐不动的肥胖成年人的身体成分和血浆代谢组学的影响。小吃组的参与者每周进行 4 天的爬楼梯冲刺运动,为期 12 周。在干预前后测量了全身和区域脂肪量、心外膜脂肪组织(EAT)、腹部内脏脂肪组织(AVFA)和皮下脂肪组织(ASFA)的脂肪面积以及血浆代谢组学数据。与对照组相比,小吃组的 EAT、AVFA 和 ASFA 改善程度更高,且有显著的交互效应(p < 0.05)。两组之间的主要差异代谢物包括异亮氨酸、甘氨酸和丝氨酸。建议的运动点心有效地减少了 AVFA 和 EAT 的数量。身体成分的变化可能与异亮氨酸、甘氨酸和丝氨酸代谢途径的改变有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Endocrine journal
Endocrine journal 医学-内分泌学与代谢
CiteScore
4.30
自引率
5.00%
发文量
224
审稿时长
1.5 months
期刊介绍: Endocrine Journal is an open access, peer-reviewed online journal with a long history. This journal publishes peer-reviewed research articles in multifaceted fields of basic, translational and clinical endocrinology. Endocrine Journal provides a chance to exchange your ideas, concepts and scientific observations in any area of recent endocrinology. Manuscripts may be submitted as Original Articles, Notes, Rapid Communications or Review Articles. We have a rapid reviewing and editorial decision system and pay a special attention to our quick, truly scientific and frequently-citable publication. Please go through the link for author guideline.
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