Comparison of Conventional IgE Assay and Measurement of Specific IgE to Haemocyanin for the Diagnosis of Adult Crab Allergy.

IF 6.3 2区医学 Q1 ALLERGY

Clinical and Experimental Allergy Pub Date : 2024-11-12 DOI:10.1111/cea.14597

Hoang Kim Tu Trinh, Kieu-Minh Le, Thanh Niem Vo Van, Duy Le Pham, Hieu Thao Nguyen, Minh Nguyet Tran Thi, Bao Yen Pham, Dinh Minh Pham

引用次数: 0

Abstract

Five potential allergens of freshwater crab (Somanniathelphusa sinensis), including hemocyanin, have been discovered. Specific IgE to haemocyanin was increased in crab-allergic than in crab-tolerant patients. The add-on of specific IgE to hemocyanin to skin prick test enhanced the specificity of the crab allergy diagnosis. IgE, immunoglobulin E; rHM, recombinant haemocyanin; sIgE, specific IgE; SPT: skin prick test.

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比较传统 IgE 检测法和血蓝蛋白特异性 IgE 检测法诊断成人螃蟹过敏。

已发现淡水蟹（Somanniathelphusa sinensis）的五种潜在过敏原，包括血蓝蛋白。对螃蟹过敏的病人对血色素的特异性 IgE 比对螃蟹耐受的病人高。在皮肤点刺试验中加入血蓝蛋白特异性 IgE 可提高螃蟹过敏诊断的特异性。IgE：免疫球蛋白 E；rHM：重组血蓝蛋白；sIgE：特异性 IgE；SPT：皮肤点刺试验。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Allergy 医学-过敏

CiteScore

10.40

自引率

9.80%

发文量

189

审稿时长

3-8 weeks

期刊介绍： Clinical & Experimental Allergy strikes an excellent balance between clinical and scientific articles and carries regular reviews and editorials written by leading authorities in their field. In response to the increasing number of quality submissions, since 1996 the journals size has increased by over 30%. Clinical & Experimental Allergy is essential reading for allergy practitioners and research scientists with an interest in allergic diseases and mechanisms. Truly international in appeal, Clinical & Experimental Allergy publishes clinical and experimental observations in disease in all fields of medicine in which allergic hypersensitivity plays a part.