Advance of Circulating Tumor Cells in the Prognosis and Management of Endometrial Cancer.

IF 1.8 4区医学 Q3 ONCOLOGY

Cancer Investigation Pub Date : 2024-11-01 Epub Date: 2024-11-12 DOI:10.1080/07357907.2024.2422607

Hongli Li, Chang Liu, Jing Wang, Feixue Xu, Yongxiu Yang, Xiaolei Liang

引用次数: 0

Abstract

Endometrial cancer (EC) is a common gynecological malignancy and its mortality has been increasing in the last twenty years. A growing body of evidence suggests that circulating tumor cells (CTCs) may provide a more complete tumor profile, facilitate the understanding of the molecular mechanism and individual management of EC patients. In this review, we presented the presence and clinical applications of CTCs and disseminated tumor cells (DTCs) in EC, particularly for EC prognosis and management, also highlighted the diagnostic value of tumor cells in urine of EC patients, aim to help researchers better focus on their study in this field.

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循环肿瘤细胞在子宫内膜癌的预后和治疗中的作用。

子宫内膜癌（EC）是一种常见的妇科恶性肿瘤，近二十年来，其死亡率不断上升。越来越多的证据表明，循环肿瘤细胞（CTCs）可提供更完整的肿瘤概况，促进对分子机制的理解和对子宫内膜癌患者的个体化治疗。在这篇综述中，我们介绍了CTCs和播散性肿瘤细胞（DTCs）在EC中的存在和临床应用，特别是对EC预后和管理的作用，还强调了EC患者尿液中肿瘤细胞的诊断价值，旨在帮助研究人员更好地专注于这一领域的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Investigation 医学-肿瘤学

CiteScore

3.80

自引率

4.20%

发文量

审稿时长

8.5 months

期刊介绍： Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.