Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa.

IF 2.3 4区医学 Q2 PATHOLOGY

American journal of clinical pathology Pub Date : 2024-11-12 DOI:10.1093/ajcp/aqae148

Jeremy W Jacobs, Brian D Adkins, Danny A Milner, Evan M Bloch, Quentin Eichbaum

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引用次数: 0

Abstract

Objectives: Inadequate laboratory infrastructure and testing capabilities are a major impediment to addressing the infectious disease burden in Africa. Therefore, the aims of this study were to characterize the clinical microbiology/infectious disease laboratory capabilities among countries in Africa.

Methods: A survey to assess the microbiological testing capabilities at hospitals, government laboratories, and free-standing public and private laboratories in African countries was developed by subject matter experts. Questions included institutional demographics and microbiology services in the broad categories of bacteriology, virology, mycology, parasitology, and rapid diagnostics/point-of-care testing. The survey was distributed using the American Society of Clinical Pathology email listserv between June and August 2022.

Results: In total, 131 unique institutions in 28 countries endorsed at least 1 type of microbiology service, with parasitology (80.9%, 106/131) and bacteriology (77.9%, 102/131) being most common, while mycology (45.0%, 59/131) and virology (45.8%, 60/131) laboratories were less prevalent. The most frequently performed bacteriology test was bacterial identification (90.2%, 92/102), followed by aerobic bacterial cultures and antimicrobial susceptibility testing (both 89.2%, 91/102). Among all clinical microbiology/infectious disease laboratories, the most commonly tested agents were HIV (90.8%, 119/131), Treponema pallidum (78.6%, 103/131), Plasmodium falciparum (76.3%, 100/131), Mycobacterium tuberculosis (76.3%, 100/131), and hepatitis C virus (74.8%, 98/131).

Conclusions: These findings provide contemporary data regarding the availability of critical infectious disease testing capabilities among institutions in Africa. These results and future additional studies will be crucial for understanding where strategic investment in the laboratory and public health infrastructure is warranted.

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非洲各机构临床微生物学和传染病检测能力调查。

目标：实验室基础设施和检测能力不足是应对非洲传染病负担的主要障碍。因此，本研究旨在了解非洲各国临床微生物学/传染病实验室能力的特点：方法：主题专家制定了一项调查，以评估非洲国家的医院、政府实验室以及独立的公共和私营实验室的微生物检测能力。问题包括机构人口统计学和微生物学服务，大类包括细菌学、病毒学、真菌学、寄生虫学和快速诊断/护理点检测。调查在 2022 年 6 月至 8 月期间通过美国临床病理学会电子邮件列表服务进行分发：共有 28 个国家的 131 家机构认可至少一种微生物学服务，其中寄生虫学（80.9%，106/131）和细菌学（77.9%，102/131）最为常见，而真菌学（45.0%，59/131）和病毒学（45.8%，60/131）实验室较少。最常进行的细菌学检验是细菌鉴定（90.2%，92/102），其次是需氧细菌培养和抗菌药物药敏试验（均为 89.2%，91/102）。在所有临床微生物学/传染病实验室中，最常检测的病原体是艾滋病毒（90.8%，119/131）、苍白链球菌（78.6%，103/131）、恶性疟原虫（76.3%，100/131）、结核分枝杆菌（76.3%，100/131）和丙型肝炎病毒（74.8%，98/131）：这些研究结果提供了有关非洲机构关键传染病检测能力可用性的最新数据。这些结果和未来的其他研究对于了解哪些领域需要对实验室和公共卫生基础设施进行战略投资至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of clinical pathology 医学-病理学

CiteScore

7.70

自引率

2.90%

发文量

367

审稿时长

3-6 weeks

期刊介绍： The American Journal of Clinical Pathology (AJCP) is the official journal of the American Society for Clinical Pathology and the Academy of Clinical Laboratory Physicians and Scientists. It is a leading international journal for publication of articles concerning novel anatomic pathology and laboratory medicine observations on human disease. AJCP emphasizes articles that focus on the application of evolving technologies for the diagnosis and characterization of diseases and conditions, as well as those that have a direct link toward improving patient care.