Exploring the association between alcohol consumption and androgenic alopecia: a systematic review and meta-analysis.

IF 2.1 4区医学 Q3 SUBSTANCE ABUSE

Alcohol and alcoholism Pub Date : 2024-09-21 DOI:10.1093/alcalc/agae076

Won Jin Yang, Jae Yong Lee, Dai Sik Ko, Eunjeong Son, Kihyuk Shin, Won Kyu Kim, Kihun Kim, Yun Hak Kim

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引用次数: 0

Abstract

Aims: Androgenetic alopecia (AGA) is widely recognized as the most common form of hair loss and can significantly affect individuals' quality of life. The association between alcohol consumption and AGA remains uncertain and controversial. Our primary objective is to investigate the relationship between alcohol consumption and AGA.

Methods: We identified studies from multiple databases, including Embase, MEDLINE, ScienceDirect, Scopus, and Web of Science, up to March 2024. For alcohol consumption, we included studies where it was defined as a categorical variable, such as Yes/No or classified by grams. For AGA, only cases that were clinically diagnosed were included. Odds ratios (ORs) and their corresponding 95% confidence intervals were extracted from the included studies. Subgroup analyses were conducted, considering factors such as gender and study design.

Results: Our findings indicated that individuals who consume alcohol had an OR of AGA compared to those who do not drink alcohol (OR, 1.40; 95% CI: .95-2.06; k = 6; I2 = 77%). In the subgroup analysis focusing on men, an OR for alopecia was observed (OR, 1.31; 95% CI: .85-2.01; k = 4; I2 = 78%). Additionally, a subgroup analysis based on study design revealed ORs of 1.93 (95% CI: 1.32-2.82; k = 3; I2 = 47%) for cross-sectional studies, and 1.69 (95% CI: 1.33-2.14; k = 2; I2 = 0%) for case-control studies.

Conclusions: Our results suggest that the effect of alcohol consumption on AGA may be less than initially assumed. Future research will require large, carefully planned cohort studies that incorporate standardized diagnostic criteria to provide more definitive insights.

Systematic review registration: CRD42022303374.

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探索饮酒与雄激素性脱发之间的关系：系统回顾与荟萃分析。

目的：雄激素性脱发（AGA）被公认为最常见的脱发形式，会严重影响个人的生活质量。饮酒与 AGA 之间的关系仍不确定，且存在争议。我们的主要目的是研究饮酒与 AGA 之间的关系：我们从多个数据库（包括 Embase、MEDLINE、ScienceDirect、Scopus 和 Web of Science）中确定了截至 2024 年 3 月的研究。对于饮酒量，我们纳入了将其定义为 "是/否 "或按克数分类等分类变量的研究。对于 AGA，只纳入临床诊断的病例。我们从纳入的研究中提取了比值比（OR）及其相应的 95% 置信区间。考虑到性别和研究设计等因素，进行了分组分析：我们的研究结果表明，与不饮酒的人相比，饮酒者的 AGA OR 为（OR，1.40；95% CI：.95-2.06；k = 6；I2 = 77%）。在以男性为重点的亚组分析中，观察到脱发的 OR 值（OR，1.31；95% CI：.85-2.01；k = 4；I2 = 78%）。此外，基于研究设计的亚组分析显示，横断面研究的OR值为1.93（95% CI：1.32-2.82；k = 3；I2 = 47%），病例对照研究的OR值为1.69（95% CI：1.33-2.14；k = 2；I2 = 0%）：我们的研究结果表明，饮酒对 AGA 的影响可能比最初假设的要小。未来的研究需要进行大规模、精心策划的队列研究，并纳入标准化诊断标准，以提供更明确的见解：CRD42022303374。

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来源期刊

Alcohol and alcoholism 医学-药物滥用

CiteScore

4.70

自引率

3.60%

发文量

审稿时长

4-8 weeks

期刊介绍： About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.