{"title":"Cracking the triple helix","authors":"Michael J. Diaz","doi":"10.1038/s41570-024-00668-1","DOIUrl":null,"url":null,"abstract":"A novel method to detect proteins interacting with triplex DNA in living cells has been developed. This approach provides new insights into triplex DNA regulation and highlights potential therapeutic targets to prevent DNA damage.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"3 1","pages":""},"PeriodicalIF":38.1000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews. Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1038/s41570-024-00668-1","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A novel method to detect proteins interacting with triplex DNA in living cells has been developed. This approach provides new insights into triplex DNA regulation and highlights potential therapeutic targets to prevent DNA damage.
期刊介绍:
Nature Reviews Chemistry is an online-only journal that publishes Reviews, Perspectives, and Comments on various disciplines within chemistry. The Reviews aim to offer balanced and objective analyses of selected topics, providing clear descriptions of relevant scientific literature. The content is designed to be accessible to recent graduates in any chemistry-related discipline while also offering insights for principal investigators and industry-based research scientists. Additionally, Reviews should provide the authors' perspectives on future directions and opinions regarding the major challenges faced by researchers in the field.