Wearable device-measured bouted and sporadic physical activity patterns and incident COPD: A prospective cohort study from UK Biobank

IF 3.9 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Public Health Pub Date : 2024-11-07 DOI:10.1016/j.puhe.2024.10.027

Qingling Yang , Tongyu Ma , Kin Cheung , Harry Haoxiang Wang , Yao Jie Xie

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引用次数: 0

Abstract

Objectives

Moderate-to-vigorous physical activity (MVPA) is associated with a reduced risk of chronic obstructive pulmonary disease (COPD), but the optimal accumulation patterns are unclear. We aimed to investigate the associations between accelerometer-measured bouted and sporadic MVPA and incident COPD in the UK Biobank.

Study design

Prospective cohort study.

Methods

We included 94161 COPD-free participants (median age of 61.74 years at baseline) from the UK Biobank who wore a wrist accelerometer. A random forest classifier was used to differentiate sporadic and bouted MVPA. Multivariable Cox proportional hazard models and restricted cubic splines were used to examine the MVPA-COPD associations.

Results

During a median follow-up of 7.95 years, 1380 incident COPD cases were identified. Bouted MVPA was inversely associated with COPD incidence in an L-shaped manner, with hazard ratios of 0.62 (95 % CI: 0.52–0.75) for intermediate vs lowest quintile and 0.43 (95 % CI: 0.34–0.55) for highest vs lowest quintile. In those with insufficient bouted MVPA, sporadic MVPA had a U-shaped association with incident COPD, with hazard ratios of 0.82 (95 %: CI: 0.67–0.99) for intermediate vs lowest quintile and 1.11 (95 % CI: 0.88–1.39) for highest vs lowest quintile.

Conclusions

Bouted MVPA is a key factor in reducing COPD incidence, while modest sporadic MVPA may offer protection when bouted MVPA is insufficient.

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可穿戴设备测量的阵发性和非阵发性体育锻炼模式与慢性阻塞性肺病发病率：英国生物数据库前瞻性队列研究。

目的：中等强度到高强度的体力活动（MVPA）与慢性阻塞性肺病（COPD）风险的降低有关，但最佳的积累模式尚不清楚。我们的目的是在英国生物库中调查加速计测量的阵发性和零星 MVPA 与慢性阻塞性肺病之间的关系：研究设计：前瞻性队列研究：我们纳入了英国生物库中94161名佩戴腕部加速度计的无慢性阻塞性肺病参与者（基线年龄中位数为61.74岁）。采用随机森林分类器区分零星和阵发性 MVPA。采用多变量 Cox 比例危险模型和限制性立方样条来研究 MVPA 与慢性阻塞性肺病的关系：结果：在中位 7.95 年的随访期间，共发现了 1380 例慢性阻塞性肺病病例。有氧运动量与慢性阻塞性肺病发病率呈 L 型反比，中间五分位数与最低五分位数的危险比为 0.62（95 % CI：0.52-0.75），最高五分位数与最低五分位数的危险比为 0.43（95 % CI：0.34-0.55）。在MVPA不足的人群中，零星MVPA与慢性阻塞性肺病的发生呈U型关系，中间五分位数与最低五分位数的危险比为0.82（95 % CI：0.67-0.99），最高五分位数与最低五分位数的危险比为1.11（95 % CI：0.88-1.39）：有节制的 MVPA 是降低慢性阻塞性肺病发病率的关键因素，而当有节制的 MVPA 不足时，适度的零星 MVPA 可提供保护。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

7.60

自引率

0.00%

发文量

280

审稿时长

37 days

期刊介绍： Public Health is an international, multidisciplinary peer-reviewed journal. It publishes original papers, reviews and short reports on all aspects of the science, philosophy, and practice of public health.