Yan Zhao, Jian Zhang, Yiru Fang, Pingxian Zhang, Hanchen Chen
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引用次数: 0
Abstract
The Structural Maintenance of Chromosomes 5/6 (SMC5/6) complex plays a pivotal role in safeguarding the structural integrity and morphology of chromosomes, thereby contributing to genomic stability-a cornerstone for normal growth and development across organisms. Beyond its fundamental role in eukaryotic DNA damage repair, recent research has broadened our understanding of SMC5/6's multifaceted functions. It has emerged as a crucial regulator not only of the cell cycle but also in developmental processes, plant immunity, and meiotic DNA damage repair. In this review, we highlight its novel roles in modulating plant growth, development, and immunity, providing fresh perspectives on how this complex might help combat DNA damage stress and orchestrate growth strategies. Furthermore, we emphasize that SMC5/6 offers a unique window into the intricate mechanisms underlying genomic maintenance, development, and stress responses, with profound implications for crop improvement.
染色体 5/6（SMC5/6）结构维持复合体在保护染色体结构完整性和形态方面发挥着关键作用，从而促进了基因组稳定性--这是生物体正常生长和发育的基石。除了在真核生物 DNA 损伤修复中的基本作用外，最近的研究拓宽了我们对 SMC5/6 多方面功能的认识。它不仅是细胞周期的关键调节因子，还是发育过程、植物免疫和减数分裂 DNA 损伤修复的关键调节因子。在这篇综述中，我们重点介绍了它在调节植物生长、发育和免疫方面的新作用，为这一复合体如何帮助对抗 DNA 损伤压力和协调生长策略提供了新的视角。此外，我们还强调，SMC5/6 为了解基因组维护、发育和应激反应的复杂机制提供了一个独特的窗口，对作物改良具有深远的影响。
期刊介绍：
Plant Physiology and Biochemistry publishes original theoretical, experimental and technical contributions in the various fields of plant physiology (biochemistry, physiology, structure, genetics, plant-microbe interactions, etc.) at diverse levels of integration (molecular, subcellular, cellular, organ, whole plant, environmental). Opinions expressed in the journal are the sole responsibility of the authors and publication does not imply the editors'' agreement.
Manuscripts describing molecular-genetic and/or gene expression data that are not integrated with biochemical analysis and/or actual measurements of plant physiological processes are not suitable for PPB. Also "Omics" studies (transcriptomics, proteomics, metabolomics, etc.) reporting descriptive analysis without an element of functional validation assays, will not be considered. Similarly, applied agronomic or phytochemical studies that generate no new, fundamental insights in plant physiological and/or biochemical processes are not suitable for publication in PPB.
Plant Physiology and Biochemistry publishes several types of articles: Reviews, Papers and Short Papers. Articles for Reviews are either invited by the editor or proposed by the authors for the editor''s prior agreement. Reviews should not exceed 40 typewritten pages and Short Papers no more than approximately 8 typewritten pages. The fundamental character of Plant Physiology and Biochemistry remains that of a journal for original results.
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