Global, regional, and national burden of ischemic stroke attributable to active smoking, 1990-2021.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2024-11-07 eCollection Date: 2024-01-01 DOI:10.18332/tid/194697

Meng Pang, Shuai Hou, Xiaoshuang Xia, Gang Wang, Yanqiang Wang, Lin Wang, Xin Li

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引用次数: 0

Abstract

Introduction: Ischemic stroke is a major global health issue, with active smoking identified as a key modifiable risk factor. This study examines the burden of ischemic stroke due to active smoking from 1990 to 2021, across different sociodemographic contexts.

Methods: Data from the Global Burden of Disease (GBD) 2021 database were used to extract information on mortality and disability-adjusted life years (DALYs) attributable to active smoking-related ischemic stroke. Countries and regions were categorized by the sociodemographic index (SDI) into five levels. Statistical analyses were conducted using R Studio, including the calculation of estimated annual percentage change (EAPC) and joinpoint regression models.

Results: In 2021, there were 342674 deaths globally due to ischemic stroke caused by active smoking, with an age-standardized mortality rate (ASMR) of 4.06 and a population-attributable fraction (PAF) of 9.54%. The number of deaths increased by 35.59% from 1990 to 2021, with males aged ≥70 years experiencing the largest increase. The global age-standardized DALY rate in 2021 was 98.29, with an overall increase in DALYs by 33.55% from 1990. Regional analysis revealed significant disparities, with the middle SDI region reporting the highest number of deaths and DALYs, while the high SDI region reported the lowest. Geographically, East Asia had the highest burden in 2021. Nationally, China had the highest number of deaths and DALYs due to smoking-related ischemic stroke.

Conclusions: This study highlights the significant global burden of ischemic stroke attributable to active smoking and the critical need for targeted smoking cessation programs and stroke prevention strategies. Despite overall declines in ASMR and age-standardized DALY rates, the burden varies significantly across different regions and sociodemographic groups. Effective public health interventions, particularly in low- to middle-SDI regions, are essential to mitigate the impact of smoking-related ischemic stroke and improve global health outcomes.

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1990-2021 年全球、地区和国家因主动吸烟造成的缺血性中风负担。

介绍：缺血性中风是一个重大的全球性健康问题，而主动吸烟被认为是一个关键的可改变的风险因素。本研究探讨了 1990 年至 2021 年不同社会人口背景下主动吸烟导致缺血性中风的负担：方法：利用 2021 年全球疾病负担（GBD）数据库中的数据，提取与主动吸烟相关的缺血性脑卒中导致的死亡率和残疾调整生命年（DALYs）信息。国家和地区按社会人口指数（SDI）分为五个等级。使用 R Studio 进行统计分析，包括计算估计年度百分比变化（EAPC）和连接点回归模型：2021 年，全球因主动吸烟导致的缺血性脑卒中死亡人数为 342674 例，年龄标准化死亡率（ASMR）为 4.06，人群可归因比例（PAF）为 9.54%。从 1990 年到 2021 年，死亡人数增加了 35.59%，其中年龄≥70 岁的男性增幅最大。2021 年全球年龄标准化残疾调整寿命年数率为 98.29，与 1990 年相比，残疾调整寿命年数总体增加了 33.55%。区域分析显示出明显的差异，中SDI区域报告的死亡人数和残疾调整寿命年数最高，而高SDI区域报告的死亡人数和残疾调整寿命年数最低。从地域上看，2021 年东亚的负担最重。就全国而言，中国因吸烟相关缺血性卒中造成的死亡人数和残疾调整寿命年数最高：本研究强调了主动吸烟对缺血性脑卒中造成的巨大全球负担，以及制定有针对性的戒烟计划和脑卒中预防策略的迫切需要。尽管 ASMR 和年龄标准化 DALY 率总体下降，但不同地区和社会人口群体的负担差异很大。有效的公共卫生干预措施，尤其是在中低收入地区，对于减轻吸烟相关缺血性卒中的影响和改善全球健康状况至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.