Corneal hypersensitivity to cold stimuli in symptomatic computer users.

IF 1.6 4区医学 Q3 OPHTHALMOLOGY

Optometry and Vision Science Pub Date : 2024-09-01 DOI:10.1097/OPX.0000000000002183

Cristian Talens-Estarelles, Blanka Golebiowski, Klaus Ehrmann, Santiago García-Lázaro, Alejandro Cerviño, Fiona Stapleton

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引用次数: 0

Abstract

Significance: Prolonged computer use may result in repeated stimulation of the ocular surface due to ocular dryness, potentially leading to alterations in its sensitivity.

Purpose: This study aimed to evaluate the relationship between ocular symptoms and corneal sensitivity to cold and mechanical stimuli in computer users.

Methods: Fifty-two young (31 ± 6 years), frequent computer users, including symptomatic and asymptomatic users, participated in this study. Mechanical and cold sensation thresholds were determined at the central cornea of one randomly selected eye of each participant using the UNSW Liquid Jet Aesthesiometer. Ocular surface symptoms and digital eye strain were assessed using the Ocular Surface Disease Index, Ocular Comfort Index, Instant Ocular Symptom Survey, and Computer Vision Syndrome Questionnaire (CVS-Q). Associations between central corneal sensation thresholds and demographic variables, patterns of digital device use, and symptom scores were analyzed using Pearson (r) or Spearman (ρ) correlations and linear regression models.

Results: Age (ρ = 0.24), CVS-Q score (ρ = -0.33), CVS-Q dry eye score (ρ = -0.28), and mechanical sensation threshold (ρ = 0.63) were significantly associated with cold sensation threshold (p≤0.04). Conversely, there were no significant relationships with Ocular Surface Disease Index, Ocular Comfort Index, or Instant Ocular Symptom Survey or with other demographic variables (p≥0.34). In multiple linear regression models, age and mechanical sensation threshold were significant predictors of cold sensitivity (p=0.04 and p<0.001, respectively) (adjusted R2 = 0.459). There were no significant correlations between mechanical sensitivity and symptom scores (p≥0.09).

Conclusions: Symptoms of digital eye strain, particularly those related to dry eye, were associated with higher corneal cold sensitivity. Corneal hypersensitivity to cold stimuli as a marker of ocular discomfort during computer use requires further investigation.

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有症状的电脑用户角膜对冷刺激的过敏性。

意义：目的：本研究旨在评估电脑使用者的眼部症状与角膜对冷刺激和机械刺激的敏感性之间的关系：52名经常使用电脑的年轻人（31 ± 6岁）参加了这项研究，其中包括有症状和无症状的使用者。使用新南威尔士大学的液体喷射麻醉仪测定了每位受试者随机选取的一只眼睛角膜中央的机械阈值和冷感阈值。使用眼表疾病指数、眼部舒适度指数、眼部症状即时调查和电脑视觉综合症问卷（CVS-Q）对眼表症状和数码眼疲劳进行了评估。使用皮尔逊（r）或斯皮尔曼（ρ）相关性和线性回归模型分析了中央角膜感觉阈值与人口统计学变量、数字设备使用模式和症状评分之间的关系：结果：年龄（ρ = 0.24）、CVS-Q 评分（ρ = -0.33）、CVS-Q 干眼评分（ρ = -0.28）和机械感觉阈值（ρ = 0.63）与冷觉阈值有显著相关性（p≤0.04）。相反，与眼表疾病指数、眼舒适度指数或即时眼部症状调查或其他人口统计学变量没有明显关系（p≥0.34）。在多元线性回归模型中，年龄和机械感觉阈值是冷敏感度的重要预测因素（p=0.04 和 p结论：数码眼疲劳症状，尤其是与干眼症有关的症状，与角膜冷敏感度较高有关。角膜对冷刺激的过敏性作为电脑使用过程中眼部不适的标志，还需要进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Optometry and Vision Science 医学-眼科学

CiteScore

2.80

自引率

7.10%

发文量

210

审稿时长

3-6 weeks

期刊介绍： Optometry and Vision Science is the monthly peer-reviewed scientific publication of the American Academy of Optometry, publishing original research since 1924. Optometry and Vision Science is an internationally recognized source for education and information on current discoveries in optometry, physiological optics, vision science, and related fields. The journal considers original contributions that advance clinical practice, vision science, and public health. Authors should remember that the journal reaches readers worldwide and their submissions should be relevant and of interest to a broad audience. Topical priorities include, but are not limited to: clinical and laboratory research, evidence-based reviews, contact lenses, ocular growth and refractive error development, eye movements, visual function and perception, biology of the eye and ocular disease, epidemiology and public health, biomedical optics and instrumentation, novel and important clinical observations and treatments, and optometric education.