Amba Esakki, Anitha Pandi, Smiline A S Girija, Vijayashree Priyadharsini Jayaseelan
{"title":"Correlating the genetic alterations and expression profile of the <i>TRA2B</i> gene in HNSCC and LUSC.","authors":"Amba Esakki, Anitha Pandi, Smiline A S Girija, Vijayashree Priyadharsini Jayaseelan","doi":"10.3897/folmed.66.e117367","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"673-681"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia medica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3897/folmed.66.e117367","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.
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