Simulated inter-filament fusion in embedded 3D printing.

IF 8.2 2区 医学 Q1 ENGINEERING, BIOMEDICAL
Leanne M Friedrich, Ross T Gunther
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引用次数: 0

Abstract

In embedded 3D printing (EMB3D), a nozzle extrudes continuous filaments inside of a viscoelastic support bath. Compared to other extrusion processes, EMB3D enables softer structures and print paths that conform better to the shape of the part, allowing for complex structures such as tissues and organs. However, strategies for high-quality dimensional accuracy and mechanical properties remain undocumented in EMB3D. This work uses computational fluid dynamics simulations in OpenFOAM to probe the underlying physics behind two processes: deformation of the printed part due to nearby nozzle motion and fusion between neighboring filaments during printing. Through simulations, we disentangle yielding from viscous dissipation, and we isolate interfacial tension effects from rheology effects, which are difficult to separate in experiments. Critically, these simulations find that disturbance and fusion are controlled by the flow of support fluid around the nozzle. To avoid part deformation, the nozzle must remain far from existing parts during non-printing moves, moreso when traveling next to the part than above the part and especially when the interfacial tension between the ink and support is non-zero. Additionally, because support can become trapped between filaments at zero interfacial tension, the spacing between filaments must be tight enough to produce over-printing, or printing too much material for the designed space. In non-Newtonian fluids, spacings for vertical walls must be even tighter than spacings for horizontal planes. At these spacings, printing a new filament sometimes creates and sometimes mitigates shape defects in the old filament. While non-zero ink-support interfacial tensions produce better inter-filament fusion than zero interfacial tension, interfacial tension also produces shape defects. Slicing algorithms that consider these unique EMB3D defects are needed to improve mechanical properties and dimensional accuracy of bioprinted constructs.

嵌入式三维打印中的模拟丝间融合。
在嵌入式三维打印(EMB3D)中,喷嘴在粘弹性支撑槽内挤出连续长丝。与其他挤出工艺相比,EMB3D 可实现更柔软的结构和更符合部件形状的打印路径,从而可打印出组织和器官等复杂结构。然而,在 EMB3D 中实现高质量尺寸精度和机械性能的策略仍未得到证实。这项工作使用 OpenFOAM 中的计算流体动力学模拟来探究两个过程背后的基本物理原理:打印部件因附近喷嘴运动而变形,以及打印过程中相邻长丝之间的融合。通过模拟,我们将屈服与粘性耗散分离开来,并将界面张力效应与流变效应分离开来,这在实验中很难分离。重要的是,这些模拟发现,扰动和融合受喷嘴周围支撑流体流动的控制。为了避免部件变形,喷嘴在非印刷移动过程中必须远离现有部件,在部件附近移动时比在部件上方移动时更要如此,尤其是当油墨和支撑液之间的界面张力不为零时。此外,由于在界面张力为零的情况下,支撑物可能会被困在细丝之间,因此细丝之间的间距必须足够紧密,以避免产生过量印刷,或在设计空间内印刷过多材料。在非牛顿流体中,垂直壁的间距必须比水平面的间距更小。在这些间距下,打印新的丝材有时会产生形状缺陷,有时则会减轻旧丝材的形状缺陷。虽然与零界面张力相比,非零油墨支撑界面张力能产生更好的丝间融合,但界面张力也会产生形状缺陷。需要考虑这些独特的 EMB3D 缺陷的切片算法,以改善生物打印结构的机械性能和尺寸精度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biofabrication
Biofabrication ENGINEERING, BIOMEDICAL-MATERIALS SCIENCE, BIOMATERIALS
CiteScore
17.40
自引率
3.30%
发文量
118
审稿时长
2 months
期刊介绍: Biofabrication is dedicated to advancing cutting-edge research on the utilization of cells, proteins, biological materials, and biomaterials as fundamental components for the construction of biological systems and/or therapeutic products. Additionally, it proudly serves as the official journal of the International Society for Biofabrication (ISBF).
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