Ultrasound-Defined Sarcopenia Independently Predicts Acute Decompensation in Advanced Chronic Liver Disease

IF 8.9 1区医学

Journal of Cachexia, Sarcopenia and Muscle Pub Date : 2024-11-11 DOI:10.1002/jcsm.13630

Juliana Gödiker, Lea Schwind, Torid Jacob, Nina Böhling, Sara Noemi Reinartz Groba, Markus Kimmann, Jörn Arne Meier, Kai-Henrik Peiffer, Jonel Trebicka, Johannes Chang, Michael Praktiknjo

引用次数: 0

Abstract

It has been shown that in patients with liver cirrhosis, sarcopenia is a predictor of acute decompensation (AD), acute-on-chronic liver failure (ACLF) and death. However, computer tomography (CT), as a suggested standard method for diagnosing sarcopenia, is resource intensive and involves radiation exposure. Therefore, in this study, we evaluate the muscle thickness of quadriceps femoris measured by ultrasound (US) as a prognostic parameter for AD and all-cause mortality in chronic liver disease.

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超声波定义的 "肌肉疏松症 "可独立预测晚期慢性肝病的急性衰竭

研究表明，在肝硬化患者中，肌肉疏松症是急性肝功能失代偿（AD）、急性慢性肝功能衰竭（ACLF）和死亡的预兆。然而，计算机断层扫描（CT）作为诊断肌肉疏松症的标准方法，需要耗费大量资源，而且会产生辐射。因此，在本研究中，我们将超声波（US）测量的股四头肌肌肉厚度作为慢性肝病患者肌少症和全因死亡率的预后参数进行评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cachexia, Sarcopenia and Muscle Medicine-Orthopedics and Sports Medicine

自引率

12.40%

发文量

期刊介绍： The Journal of Cachexia, Sarcopenia, and Muscle is a prestigious, peer-reviewed international publication committed to disseminating research and clinical insights pertaining to cachexia, sarcopenia, body composition, and the physiological and pathophysiological alterations occurring throughout the lifespan and in various illnesses across the spectrum of life sciences. This journal serves as a valuable resource for physicians, biochemists, biologists, dieticians, pharmacologists, and students alike.