Ghasem Rezanejade Bardajee, Nastaran Dianatnejad, Nosrat O. Mahmoodi, Hossein Mahmoodain
{"title":"Mechanical properties and development of silver Nanoparticle-enhanced Alginate-polyacrylamide double network Hydrogel","authors":"Ghasem Rezanejade Bardajee, Nastaran Dianatnejad, Nosrat O. Mahmoodi, Hossein Mahmoodain","doi":"10.1007/s10965-024-04188-w","DOIUrl":null,"url":null,"abstract":"<div><p>This study investigates the enhancement of mechanical properties in a sodium alginate-polyacrylamide double network (DN) nanocomposite hydrogel enhanced with silver nanoparticles (Alg-g-PAAm/nAg). This hydrogel utilizes both thermal and ionic cross-linking methods (MBA and CaCl<sub>2</sub>) to develop a robust matrix with outstanding mechanical and thermal properties. The Alg-g-PAAm/nAg DN nanocomposite hydrogel demonstrated a fracture stress of 1255 kPa, an elastic modulus of 200 kPa, and an exceptional toughness value of 520,000 kJ/m³. Furthermore, the material’s response to swelling in various pH and temperatures was analyzed through swelling studies, revealing significant pH sensitivity. The incorporation of silver nanoparticles (Ag NPs) within the nanocomposite significantly enhanced both its mechanical strength and stability, as well as its antibacterial performance. Antimicrobial assays against Staphylococcus aureus and Escherichia coli demonstrated pronounced inhibition zones, indicating the hydrogel’s potent antibacterial properties. This dual enhancement makes the composite highly suitable for various demanding biomedical applications. The comprehensive analytical techniques employed, including FT-IR, FE-SEM, TEM, and TGA, confirmed the successful integration of the Ag NPs within the nanocomposite structure and underscored the material’s potential in fields such as tissue engineering, drug delivery systems, and advanced wound dressings.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":658,"journal":{"name":"Journal of Polymer Research","volume":"31 11","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Polymer Research","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10965-024-04188-w","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
This study investigates the enhancement of mechanical properties in a sodium alginate-polyacrylamide double network (DN) nanocomposite hydrogel enhanced with silver nanoparticles (Alg-g-PAAm/nAg). This hydrogel utilizes both thermal and ionic cross-linking methods (MBA and CaCl2) to develop a robust matrix with outstanding mechanical and thermal properties. The Alg-g-PAAm/nAg DN nanocomposite hydrogel demonstrated a fracture stress of 1255 kPa, an elastic modulus of 200 kPa, and an exceptional toughness value of 520,000 kJ/m³. Furthermore, the material’s response to swelling in various pH and temperatures was analyzed through swelling studies, revealing significant pH sensitivity. The incorporation of silver nanoparticles (Ag NPs) within the nanocomposite significantly enhanced both its mechanical strength and stability, as well as its antibacterial performance. Antimicrobial assays against Staphylococcus aureus and Escherichia coli demonstrated pronounced inhibition zones, indicating the hydrogel’s potent antibacterial properties. This dual enhancement makes the composite highly suitable for various demanding biomedical applications. The comprehensive analytical techniques employed, including FT-IR, FE-SEM, TEM, and TGA, confirmed the successful integration of the Ag NPs within the nanocomposite structure and underscored the material’s potential in fields such as tissue engineering, drug delivery systems, and advanced wound dressings.
期刊介绍:
Journal of Polymer Research provides a forum for the prompt publication of articles concerning the fundamental and applied research of polymers. Its great feature lies in the diversity of content which it encompasses, drawing together results from all aspects of polymer science and technology.
As polymer research is rapidly growing around the globe, the aim of this journal is to establish itself as a significant information tool not only for the international polymer researchers in academia but also for those working in industry. The scope of the journal covers a wide range of the highly interdisciplinary field of polymer science and technology, including:
polymer synthesis;
polymer reactions;
polymerization kinetics;
polymer physics;
morphology;
structure-property relationships;
polymer analysis and characterization;
physical and mechanical properties;
electrical and optical properties;
polymer processing and rheology;
application of polymers;
supramolecular science of polymers;
polymer composites.