Macrophages support pancreatic development

IF 31 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Senegal Carty
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引用次数: 0

Abstract Image

巨噬细胞支持胰腺发育
治疗糖尿病的胰腺组织移植工程需要了解不同细胞类型是如何调控胰腺发育的。为了研究巨噬细胞能否支持胰腺内分泌细胞在体外的存活和发育,研究人员将人类胚胎干细胞分化成胰腺内分泌细胞和巨噬细胞,并将这两种细胞共培养。与不培养巨噬细胞的内分泌细胞相比,与巨噬细胞共同培养的内分泌细胞的存活率更高。与巨噬细胞共培养还能促进内分泌细胞增殖并分化成β样细胞。
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来源期刊
Nature Reviews Endocrinology
Nature Reviews Endocrinology 医学-内分泌学与代谢
CiteScore
42.00
自引率
0.70%
发文量
158
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Endocrinology aspires to be the foremost platform for reviews and commentaries catering to the scientific communities it serves. The journal aims to publish articles characterized by authority, accessibility, and clarity, enhanced with easily understandable figures, tables, and other visual aids. The goal is to offer an unparalleled service to authors, referees, and readers, striving to maximize the usefulness and impact of each article. Nature Reviews Endocrinology publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians in the fields of endocrinology and metabolism. Its broad scope ensures that the work it publishes reaches the widest possible audience.
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